Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate

From GWAS to biology: lessons from FTO

(2011) Yi-Chun Loraine Tung et al.   Annals of the New York Academy of Sciences

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Crystal structure of the FTO protein reveals basis for its substrate specificity

(2010) Zhifu Han et al.   NATURE

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats

(2010) Yi-Chun Loraine Tung et al.   PLoS One

The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice

(2010) Xue Gao et al.   PLoS One

Loss-of-Function Mutation in the Dioxygenase-Encoding FTO Gene Causes Severe Growth Retardation and Multiple Malformations

(2009) Sarah Boissel et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Effects of α-ketoglutarate on neutrophil intracellular amino and α-keto acid profiles and ROS production

(2009) Jörg Mühling et al.   AMINO ACIDS

Endoribonuclease activity of human apurinic/apyrimidinic endonuclease 1 revealed by a real-time fluorometric assay

(2009) Sang-Eun Kim et al.   ANALYTICAL BIOCHEMISTRY

Prevalence of Loss-of-Function FTO Mutations in Lean and Obese Individuals

(2009) D. Meyre et al.   DIABETES

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

A Mouse Model for the Metabolic Effects of the Human Fat Mass and Obesity Associated FTO Gene

(2009) Chris Church et al.   PLoS Genetics

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

(2008) Guifang Jia et al.   FEBS LETTERS