Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes

O-GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver

(2011) C. Guinez et al.   DIABETES

Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis

(2011) C. Arden et al.   DIABETES

An extended Myc network contributes to glucose homeostasis in cancer and diabetes

(2011) Christopher et al.   Frontiers in Bioscience-Landmark

Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver

(2011) Renaud Dentin et al.   JOURNAL OF HEPATOLOGY

Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP)

(2010) Ming V. Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor α (LXRα) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1

(2010) Aldo Grefhorst et al.   BIOCHEMICAL JOURNAL

Glucose Controls Nuclear Accumulation, Promoter Binding, and Transcriptional Activity of the MondoA-Mlx Heterodimer

(2010) C. W. Peterson et al.   MOLECULAR AND CELLULAR BIOLOGY

An enzymatic fluorimetric assay for glucose-6-phosphate: Application in an in vitro Warburg-like effect

(2009) Aiping Zhu et al.   ANALYTICAL BIOCHEMISTRY

Glucose-6-phosphatase Catalytic Subunit Gene Family

(2009) John C. Hutton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases

(2009) Abdullah Yalcin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation

(2009) X. Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic β-cells

(2008) Catherine Arden et al.   BIOCHEMICAL JOURNAL

Selective versus Total Insulin Resistance: A Pathogenic Paradox

(2008) Michael S. Brown et al.   Cell Metabolism

Regulation of Nuclear Import/Export of Carbohydrate Response Element-binding Protein (ChREBP)

(2008) Haruhiko Sakiyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucose Activates ChREBP by Increasing Its Rate of Nuclear Entry and Relieving Repression of Its Transcriptional Activity

(2008) Michael N. Davies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic Glucose Sensing via the CREB Coactivator CRTC2

(2008) R. Dentin et al.   SCIENCE