Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding

Conformation-independent structural comparison of macromolecules withProSMART

(2014) Robert A. Nicholls et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Diversity of Eukaryotic Membrane Cytochrome P450s

(2013) Eric F. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins

(2013) S. C. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MOLE 2.0: advanced approach for analysis of biomacromolecular channels

(2013) David Sehnal et al.   Journal of Cheminformatics

Use of knowledge-based restraints inphenix.refineto improve macromolecular refinement at low resolution

(2012) Jeffrey J. Headd et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Conformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed upon Binding Multiple Amlodipine Molecules

(2012) Manish B. Shah et al.   BIOCHEMISTRY

Three-dimensional Structure of Steroid 21-Hydroxylase (Cytochrome P450 21A2) with Two Substrates Reveals Locations of Disease-associated Variants

(2012) Bin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Human Cytochrome P450 2D6 with Prinomastat Bound

(2012) An Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Binding and Access Channel in Human Cytochrome P450 2A6 and 2A13 Enzymes

(2012) Natasha M. DeVore et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Metabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s

(2009) Bo Wen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme

(2009) Bo Wang et al.   DRUG METABOLISM REVIEWS

Crystal Structure of CYP24A1, a Mitochondrial Cytochrome P450 Involved in Vitamin D Metabolism

(2009) Andrew J. Annalora et al.   JOURNAL OF MOLECULAR BIOLOGY