A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3)

Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3

(2011) Johnthan Gordon et al.   BMC BIOCHEMISTRY

FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins

(2011) Daniel B Roche et al.   BMC BIOINFORMATICS

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

(2011) Beatrice M Filippi et al.   EMBO JOURNAL

Hydrophobic Motif Phosphorylation Is Not Required for Activation Loop Phosphorylation of p70 Ribosomal Protein S6 Kinase 1 (S6K1)

(2011) Malik M. Keshwani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCM3/PDCD10 Heterodimerizes with Germinal Center Kinase III (GCKIII) Proteins Using a Mechanism Analogous to CCM3 Homodimerization

(2011) Derek F. Ceccarelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inosine Augments the Effects of a Nogo Receptor Blocker and of Environmental Enrichment to Restore Skilled Forelimb Use after Stroke

(2011) L. Zai et al.   JOURNAL OF NEUROSCIENCE

The IntFOLD server: an integrated web resource for protein fold recognition, 3D model quality assessment, intrinsic disorder prediction, domain prediction and ligand binding site prediction

(2011) D. B. Roche et al.   NUCLEIC ACIDS RESEARCH

Structures of human MST3 kinase in complex with adenine, ADP and Mn2+

(2010) Tzu-Ping Ko et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl− cotransport activity

(2010) Kenneth B. Gagnon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Post-translational myristoylation: Fat matters in cellular life and death

(2010) Dale D.O. Martin et al.   BIOCHIMIE

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active

(2010) Peter H. Sugden et al.   CELLULAR SIGNALLING

Recent insights into cerebral cavernous malformations: the molecular genetics of CCM

(2010) Florence Riant et al.   FEBS Journal

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation

(2010) M. Fidalgo et al.   JOURNAL OF CELL SCIENCE

CCM3 signaling through sterile 20–like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations

(2010) Xiangjian Zheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Emerging New Roles of GM130, a cis-Golgi Matrix Protein, in Higher Order Cell Functions

(2010) Nobuhiro Nakamura   JOURNAL OF PHARMACOLOGICAL SCIENCES

Structural Comparison of Human Mammalian Ste20-Like Kinases

(2010) Christopher J. Record et al.   PLoS One

Rapid model quality assessment for protein structure predictions using the comparison of multiple models without structural alignments

(2009) L. J. McGuffin et al.   BIOINFORMATICS

Mammalian sterile 20-like kinase 3 (MST3) mediates oxidative-stress-induced cell death by modulating JNK activation

(2009) Ce‑Belle Chen et al.   BIOSCIENCE REPORTS

Mammalian Ste20-like protein kinase 3 induces a caspase-independent apoptotic pathway

(2009) Chia-Ying Lin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of Expression of the Rat Orthologue of Mouse Double Minute 2 (MDM2) by H2O2-induced Oxidative Stress in Neonatal Rat Cardiac Myocytes

(2009) Sampsa Pikkarainen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Large-scale Proteomics Analysis of the Human Kinome

(2009) Felix S. Oppermann et al.   MOLECULAR & CELLULAR PROTEOMICS

Mst3b, an Ste20-like kinase, regulates axon regeneration in mature CNS and PNS pathways

(2009) Barbara Lorber et al.   NATURE NEUROSCIENCE

The mammalian family of sterile 20p-like protein kinases

(2009) Eric Delpire   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

ATP and MO25α Regulate the Conformational State of the STRADα Pseudokinase and Activation of the LKB1 Tumour Suppressor

(2009) Elton Zeqiraj et al.   PLOS BIOLOGY

Intrinsic disorder prediction from the analysis of multiple protein fold recognition models

(2008) Liam J. McGuffin   BIOINFORMATICS

Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: Activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors

(2008) Stephen J. Fuller et al.   CELLULAR SIGNALLING

WD-40 repeat protein SG2NA has multiple splice variants with tissue restricted and growth responsive properties

(2008) Mishra Sanghamitra et al.   GENE

SOK1 Translocates from the Golgi to the Nucleus upon Chemical Anoxia and Induces Apoptotic Cell Death

(2008) Emilio Nogueira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TiO2-Based Phosphoproteomic Analysis of the Plasma Membrane and the Effects of Phosphatase Inhibitor Treatment

(2008) Tine E. Thingholm et al.   JOURNAL OF PROTEOME RESEARCH

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

(2008) Marilyn Goudreault et al.   MOLECULAR & CELLULAR PROTEOMICS

STRADα Regulates LKB1 Localization by Blocking Access to Importin-α, and by Association with Crm1 and Exportin-7

(2008) Julia Dorfman et al.   MOLECULAR BIOLOGY OF THE CELL

Kinase-Selective Enrichment Enables Quantitative Phosphoproteomics of the Kinome across the Cell Cycle

(2008) Henrik Daub et al.   MOLECULAR CELL

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog

(2007) Dale D. O. Martin et al.   FASEB JOURNAL