Evidence for a link between histone deacetylation and Ca2+homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

(2012) Shigetomo Fukuhara et al.   JOURNAL OF CLINICAL INVESTIGATION

Photolysis of caged sphingosine-1-phosphate induces barrier enhancement and intracellular activation of lung endothelial cell signaling pathways

(2011) Peter V. Usatyuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Tissue Factor Pathway Inhibitor Attenuates the Progression of Malignant Pleural Mesothelioma in Nude Mice

(2011) LaTerrica Williams et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis

(2011) Jeffrey A. Cohen et al.   ANNALS OF NEUROLOGY

Regulation of Mammalian Physiology, Development, and Disease by the Sphingosine 1-Phosphate and Lysophosphatidic Acid Receptors

(2011) Victoria A. Blaho et al.   CHEMICAL REVIEWS

BACE1 Activity Is Modulated by Cell-Associated Sphingosine-1-Phosphate

(2011) N. Takasugi et al.   JOURNAL OF NEUROSCIENCE

HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells

(2011) Claire Jacob et al.   NATURE NEUROSCIENCE

Sphingosine-1-phosphate signaling and its role in disease

(2011) Michael Maceyka et al.   TRENDS IN CELL BIOLOGY

Examination of the expanding pathways for the regulation of p21 expression and activity

(2010) Yong-Sam Jung et al.   CELLULAR SIGNALLING

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

(2010) Graham M. Strub et al.   FASEB JOURNAL

Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect

(2010) Michael Dickinson et al.   INVESTIGATIONAL NEW DRUGS

Sphingosine 1-Phosphate Lyase Deficiency Disrupts Lipid Homeostasis in Liver

(2010) Meryem Bektas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

(2010) Sergio E. Alvarez et al.   NATURE

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

(2010) J. Chun et al.   PHARMACOLOGICAL REVIEWS

Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism

(2010) Florence Bourquin et al.   STRUCTURE

Regulation of sphingosine kinase and sphingolipid signaling

(2010) Stuart M. Pitson   TRENDS IN BIOCHEMICAL SCIENCES

Sphingosine-1-phosphate and immune regulation: trafficking and beyond

(2010) Hongbo Chi   TRENDS IN PHARMACOLOGICAL SCIENCES

The Plasma Membrane Ca2+ ATPase and the Plasma Membrane Sodium Calcium Exchanger Cooperate in the Regulation of Cell Calcium

(2010) M. Brini et al.   Cold Spring Harbor Perspectives in Biology

Gαq-mediated plasma membrane translocation of sphingosine kinase-1 and cross-activation of S1P receptors

(2009) Michael ter Braak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CERT-mediated trafficking of ceramide

(2009) Kentaro Hanada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Disruption of Sphingosine 1-Phosphate Lyase Confers Resistance to Chemotherapy and Promotes Oncogenesis through Bcl-2/Bcl-xL Upregulation

(2009) S. Colie et al.   CANCER RESEARCH

Sphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protection

(2009) K. Sattler et al.   CARDIOVASCULAR RESEARCH

Enhanced Ca2+ storage in sphingosine-1-phosphate lyase-deficient fibroblasts

(2009) Ralf Frederik Claas et al.   CELLULAR SIGNALLING

Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes

(2009) Sangeetha Chandrasekaran et al.   FASEB JOURNAL

Discontinued Postnatal Thymocyte Development in Sphingosine 1-Phosphate-Lyase-Deficient Mice

(2009) C. Weber et al.   JOURNAL OF IMMUNOLOGY

Lipids as targets for novel anti-inflammatory therapies

(2009) Andrea Huwiler et al.   PHARMACOLOGY & THERAPEUTICS

Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions

(2009) Peter Vogel et al.   PLoS One

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

HDAC2: a critical factor in health and disease

(2009) Oliver H. Krämer   TRENDS IN PHARMACOLOGICAL SCIENCES

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

(2008) Nagma Khan et al.   BIOCHEMICAL JOURNAL

Sphingosine-1-phosphate lyase in development and disease: Sphingolipid metabolism takes flight

(2008) H FYRST   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Biological roles of lysophospholipid receptors revealed by genetic null mice: An update

(2008) J CHOI   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo

(2008) M. Fournel et al.   MOLECULAR CANCER THERAPEUTICS