Glucan particles for selective delivery of siRNA to phagocytic cells in mice

Macrophages and Tissue Injury: Agents of Defense or Destruction?

(2011) Debra L. Laskin et al.   Annual Review of Pharmacology and Toxicology

Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape

(2011) René Bartz et al.   BIOCHEMICAL JOURNAL

Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice

(2011) Andrea Beyerle et al.   JOURNAL OF CONTROLLED RELEASE

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Polymer-related off-target effects in non-viral siRNA delivery

(2010) Olivia M. Merkel et al.   BIOMATERIALS

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE

STAT3 Silencing in Dendritic Cells by siRNA Polyplexes Encapsulated in PLGA Nanoparticles for the Modulation of Anticancer Immune Response

(2010) Aws Alshamsan et al.   MOLECULAR PHARMACEUTICS

Novel RNA-based Strategies for Therapeutic Gene Silencing

(2010) Christopher R Sibley et al.   MOLECULAR THERAPY

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

Delivery of Macromolecules Using Arginine-Rich Cell-Penetrating Peptides: Ways to Overcome Endosomal Entrapment

(2009) Ayman El-Sayed et al.   AAPS Journal

Silencing of proinflammatory genes targeted to peritoneal-residing macrophages using siRNA encapsulated in biodegradable microspheres

(2009) Tali Brunner et al.   BIOMATERIALS

A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation

(2009) X. Zheng et al.   BLOOD

RNAi-based therapeutics-current status, challenges and prospects

(2009) Katrin Tiemann et al.   EMBO Molecular Medicine

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

(2009) Myriam Aouadi et al.   NATURE

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

(2009) Marcin Kortylewski et al.   NATURE BIOTECHNOLOGY

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Solid polymeric microparticles enhance the delivery of siRNA to macrophages in vivo

(2009) S. Lee et al.   NUCLEIC ACIDS RESEARCH

High Efficiency Lipid-Based siRNA Transfection of Adipocytes in Suspension

(2009) Gail Kilroy et al.   PLoS One

Characterization of Multilayered Nanoparticles Encapsulated in Yeast Cell Wall Particles for DNA Delivery

(2008) Ernesto R. Soto et al.   BIOCONJUGATE CHEMISTRY

Chitosan/siRNA Nanoparticle–mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model

(2008) Kenneth A Howard et al.   MOLECULAR THERAPY

A New Potent Secondary Amphipathic Cell–penetrating Peptide for siRNA Delivery Into Mammalian Cells

(2008) Laurence Crombez et al.   MOLECULAR THERAPY

Novel pharmacological strategies for driving inflammatory cell apoptosis and enhancing the resolution of inflammation

(2008) John M. Hallett et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Efficient delivery of siRNA using dendritic poly(l-lysine) for loss-of-function analysis

(2007) Yusuke Inoue et al.   JOURNAL OF CONTROLLED RELEASE