Retinaldehyde is a substrate for human aldo–keto reductases of the 1C subfamily

Retinoids, Retinoic Acid Receptors, and Cancer

(2011) Xiao-Han Tang et al.   Annual Review of Pathology-Mechanisms of Disease

From carrot to clinic: an overview of the retinoic acid signaling pathway

(2010) Maria Theodosiou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identification of 9-cis-retinoic acid as a pancreas-specific autacoid that attenuates glucose-stimulated insulin secretion

(2010) M. A. Kane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Steroid Hormone Transforming Aldo-Keto Reductases and Cancer

(2009) Trevor M. Penning et al.   Annals of the New York Academy of Sciences

Induction of neoplastic transformation by ectopic expression of human aldo-keto reductase 1C isoforms in NIH3T3 cells

(2009) Chia-Wen Chien et al.   CARCINOGENESIS

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival

(2009) Yarí E. Marín et al.   EXPERIMENTAL DERMATOLOGY

The endogenous retinoid metaboliteS-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling bothin vitroandin vivo

(2009) Jan P. Schuchardt et al.   FEBS Journal

Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer

(2009) Michael C. Byrns et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance

(2009) Zachary W. Veitch et al.   Pharmacogenetics and Genomics

Combined Bezafibrate and Medroxyprogesterone Acetate: Potential Novel Therapy for Acute Myeloid Leukaemia

(2009) Farhat L. Khanim et al.   PLoS One

Medium- and short-chain dehydrogenase/reductase gene and protein families

(2008) X. Parés et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aldo-keto reductases from the AKR1B subfamily: Retinoid specificity and control of cellular retinoic acid levels

(2008) F. Xavier Ruiz et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dΔ12,14,PGJ2

(2008) R E Hayden et al.   LEUKEMIA

AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells

(2008) Shaobin Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies

(2007) Michael C. Byrns et al.   BIOCHEMICAL PHARMACOLOGY