Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies

Structural Basis for Recognition of Urokinase-type Plasminogen Activator by Plasminogen Activator Inhibitor-1

(2011) Zhonghui Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutralisation of uPA with a Monoclonal Antibody Reduces Plasmin Formation and Delays Skin Wound Healing in tPA-Deficient Mice

(2010) Annika Jögi et al.   PLoS One

Comparative Analysis of Metastasis Variants Derived from Human Prostate Carcinoma Cells

(2009) Erin M. Conn et al.   AMERICAN JOURNAL OF PATHOLOGY

Nonproteolytic Induction of Catalytic Activity into the Single-Chain Form of Urokinase-Type Plasminogen Activator by Dipeptides

(2009) Kenneth A. Bøtkjær et al.   BIOCHEMISTRY

Biochemical properties of plasminogen activator inhibitor-1

(2009) Daniel Miotto Dupont   Frontiers in Bioscience-Landmark

Unraveling the Allosteric Mechanism of Serine Protease Inhibition by an Antibody

(2009) Rajkumar Ganesan et al.   STRUCTURE

A Novel Mode of Intervention with Serine Protease Activity

(2008) Grant E. Blouse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibody-mediated Targeting of the Urokinase-type Plasminogen Activator Proteolytic Function Neutralizes Fibrinolysisin Vivo

(2008) Ida K. Lund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Peptide Accelerating the Conversion of Plasminogen Activator Inhibitor-1 to an Inactive Latent State

(2008) L. Mathiasen et al.   MOLECULAR PHARMACOLOGY

High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: A new tool for detailed interaction studies and modeling

(2008) Jan K. Jensen et al.   PROTEIN SCIENCE