WD Repeat-containing Protein 5 (WDR5) Localizes to the Midbody and Regulates Abscission

Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex

(2014) J. Dias et al.   GENES & DEVELOPMENT

A Non-Active-Site SET Domain Surface Crucial for the Interaction of MLL1 and the RbBP5/Ash2L Heterodimer within MLL Family Core Complexes

(2014) Stephen A. Shinsky et al.   JOURNAL OF MOLECULAR BIOLOGY

ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4

(2014) Sigrid B. Thoresen et al.   NATURE CELL BIOLOGY

A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia

(2014) Aamir Ali et al.   NUCLEIC ACIDS RESEARCH

Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1

(2014) Su Qin et al.   Nature Communications

Quantitative Dissection and Stoichiometry Determination of the Human SET1/MLL Histone Methyltransferase Complexes

(2013) R. van Nuland et al.   MOLECULAR AND CELLULAR BIOLOGY

Drosophila SETs Its Sights on Cancer: Trr/MLL3/4 COMPASS-Like Complexes in Development and Disease

(2013) Marc Alard Morgan et al.   MOLECULAR AND CELLULAR BIOLOGY

Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission

(2013) Matthew K. Martz et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations in Mll2, an H3K4 Methyltransferase, Result in Insulin Resistance and Impaired Glucose Tolerance in Mice

(2013) Michelle Goldsworthy et al.   PLoS One

ESCRT-III Assembly and Cytokinetic Abscission Are Induced by Tension Release in the Intercellular Bridge

(2013) J. Lafaurie-Janvore et al.   SCIENCE

ALKBH4-dependent demethylation of actin regulates actomyosin dynamics

(2013) Ming-Ming Li et al.   Nature Communications

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Cytokinesis in Animal Cells

(2012) Rebecca A. Green et al.   Annual Review of Cell and Developmental Biology

WRAD: enabler of the SET1-family of H3K4 methyltransferases

(2012) P. Ernst et al.   Briefings in Functional Genomics

Membrane dynamics during cytokinesis

(2012) John A Schiel et al.   CURRENT OPINION IN CELL BIOLOGY

Centralspindlin: At the heart of cytokinesis

(2012) Erin A. White et al.   Cytoskeleton

Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases

(2012) Venkatasubramanian Dharmarajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytokinesis microtubule organisers at a glance

(2012) K.-Y. Lee et al.   JOURNAL OF CELL SCIENCE

Human Mob1 proteins are required for cytokinesis by controlling microtubule stability

(2012) Claudia Florindo et al.   JOURNAL OF CELL SCIENCE

High-Affinity, Small-Molecule Peptidomimetic Inhibitors of MLL1/WDR5 Protein–Protein Interaction

(2012) Hacer Karatas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Midbody assembly and its regulation during cytokinesis

(2012) Chi-Kuo Hu et al.   MOLECULAR BIOLOGY OF THE CELL

HIPK2 Controls Cytokinesis and Prevents Tetraploidization by Phosphorylating Histone H2B at the Midbody

(2012) Cinzia Rinaldo et al.   MOLECULAR CELL

FIP3-endosome-dependent formation of the secondary ingression mediates ESCRT-III recruitment during cytokinesis

(2012) John A. Schiel et al.   NATURE CELL BIOLOGY

Molecular control of animal cell cytokinesis

(2012) Juan Pablo Fededa et al.   NATURE CELL BIOLOGY

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Immunolabeling artifacts and the need for live-cell imaging

(2012) Ulrike Schnell et al.   NATURE METHODS

The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases

(2012) Pamela Zhang et al.   NUCLEIC ACIDS RESEARCH

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains

(2011) Hao Jiang et al.   CELL

Endocytic membrane fusion and buckling-induced microtubule severing mediate cell abscission

(2011) J. A. Schiel et al.   JOURNAL OF CELL SCIENCE

Cytokinesis, ploidy and aneuploidy

(2011) Benjamin Lacroix et al.   JOURNAL OF PATHOLOGY

X-Linked Mental Retardation Gene CUL4B Targets Ubiquitylation of H3K4 Methyltransferase Component WDR5 and Regulates Neuronal Gene Expression

(2011) Tadashi Nakagawa et al.   MOLECULAR CELL

Mitotic Spindle Proteomics in Chinese Hamster Ovary Cells

(2011) Mary Kate Bonner et al.   PLoS One

Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

(2011) N. Elia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1

(2010) Zain Odho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission

(2010) Mathew P. Estey et al.   JOURNAL OF CELL BIOLOGY

Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome

(2010) Sarah B Ng et al.   NATURE GENETICS

Identification of a Deubiquitinating Enzyme as a Novel AGS3-Interacting Protein

(2010) Zhuojin Xu et al.   PLoS One

An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

(2010) Fang Cao et al.   PLoS One

Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance

(2010) E. Morita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WD40 proteins propel cellular networks

(2010) Christian U. Stirnimann et al.   TRENDS IN BIOCHEMICAL SCIENCES

Aurora B-Mediated Abscission Checkpoint Protects against Tetraploidization

(2009) Patrick Steigemann et al.   CELL

A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking

(2009) Zhuojin Xu et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks

(2009) Stacey M. Southall et al.   MOLECULAR CELL

Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells

(2009) Daniel A. Lim et al.   NATURE

WDR5, a complexed protein

(2009) Raymond C Trievel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF- B activation

(2009) Y.-Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokinetic abscission: cellular dynamics at the midbody

(2009) Patrick Steigemann et al.   TRENDS IN CELL BIOLOGY

Final Stages of Cytokinesis and Midbody Ring Formation Are Controlled by BRUCE

(2008) Christian Pohl et al.   CELL

Dynamic protein methylation in chromatin biology

(2008) S. S. Ng et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

Structure of WDR5 Bound to Mixed Lineage Leukemia Protein-1 Peptide

(2008) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WDR5 Interacts with Mixed Lineage Leukemia (MLL) Protein via the Histone H3-binding Pocket

(2008) Ji-Joon Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Conserved Arginine-containing Motif Crucial for the Assembly and Enzymatic Activity of the Mixed Lineage Leukemia Protein-1 Core Complex

(2008) Anamika Patel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Decision tree–driven tandem mass spectrometry for shotgun proteomics

(2008) Danielle L Swaney et al.   NATURE METHODS

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

(2008) Dong Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Spastin Couples Microtubule Severing to Membrane Traffic in Completion of Cytokinesis and Secretion

(2008) James W. Connell et al.   TRAFFIC