Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Loss of HDAC5 Impairs Memory Function: Implications for Alzheimer's Disease

(2018) Roberto Carlos Agis-Balboa et al.   JOURNAL OF ALZHEIMERS DISEASE

The transcriptional repressor HDAC7 promotes apoptosis and c-Myc downregulation in particular types of leukemia and lymphoma

(2015) B Barneda-Zahonero et al.   Cell Death & Disease

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease

(2013) Roland W. Bürli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

(2013) Christopher J. Millard et al.   MOLECULAR CELL

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

(2013) Michal Mielcarek et al.   PLOS BIOLOGY

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

(2012) Peter J. Watson et al.   NATURE

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

(2012) Céline Bellenguez et al.   NATURE GENETICS

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

(2011) Jasmeen Oberoi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Physiological Roles of Class I HDAC Complex and Histone Demethylase

(2010) Tomohiro Hayakawa et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

A Redox-Dependent Pathway for Regulating Class II HDACs and Cardiac Hypertrophy

(2008) Tetsuro Ago et al.   CELL

Structural and Functional Analysis of the Human HDAC4 Catalytic Domain Reveals a Regulatory Structural Zinc-binding Domain

(2008) Matthew J. Bottomley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

(2008) Fiona L. Scott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY