Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases fromSaccharomyces cerevisiae

Profiling the orphan enzymes

(2014) Maria Sorokina et al.   Biology Direct

Identification of Novel Coxiella burnetii Icm/Dot Effectors and Genetic Analysis of Their Involvement in Modulating a Mitogen-Activated Protein Kinase Pathway

(2014) Ziv Lifshitz et al.   INFECTION AND IMMUNITY

Yeast Nem1-Spo7 Protein Phosphatase Activity on Pah1 Phosphatidate Phosphatase Is Specific for the Pho85-Pho80 Protein Kinase Phosphorylation Sites

(2014) Wen-Min Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzyme Promiscuity: Engine of Evolutionary Innovation

(2014) Chetanya Pandya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

(2014) Thomas M. Carlile et al.   NATURE

A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism

(2013) Aymeric Goyer et al.   BIOCHEMICAL JOURNAL

Small RNA-Mediated Activation of Sugar Phosphatase mRNA Regulates Glucose Homeostasis

(2013) Kai Papenfort et al.   CELL

Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides

(2013) Anatoli Tchigvintsev et al.   CHEMISTRY & BIOLOGY

Evolutionary and Structural Analyses of Mammalian Haloacid Dehalogenase-type Phosphatases AUM and Chronophin Provide Insight into the Basis of Their Different Substrate Specificities

(2013) Annegrit Seifried et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronophin Dimerization Is Required for Proper Positioning of Its Substrate Specificity Loop

(2013) Christian Kestler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ER exit sites are physical and functional core autophagosome biogenesis components

(2013) Martin Graef et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleotide degradation and ribose salvage in yeast

(2013) Y.-F. Xu et al.   Molecular Systems Biology

Saccharomycesgenome database provides new regulation data

(2013) Maria C. Costanzo et al.   NUCLEIC ACIDS RESEARCH

Rational and Evolutionary Engineering Approaches Uncover a Small Set of Genetic Changes Efficient for Rapid Xylose Fermentation in Saccharomyces cerevisiae

(2013) Soo Rin Kim et al.   PLoS One

The COMBREX Project: Design, Methodology, and Initial Results

(2013) Brian P. Anton et al.   PLOS BIOLOGY

Deletion of the PHO13 gene in Saccharomyces cerevisiae improves ethanol production from lignocellulosic hydrolysate in the presence of acetic and formic acids, and furfural

(2012) Keisuke Fujitomi et al.   BIORESOURCE TECHNOLOGY

Divergence of Structure and Function in the Haloacid Dehalogenase Enzyme Superfamily:Bacteroides thetaiotaomicronBT2127 Is an Inorganic Pyrophosphatase

(2011) Hua Huang et al.   BIOCHEMISTRY

The Enzyme Function Initiative

(2011) John A. Gerlt et al.   BIOCHEMISTRY

Pyridoxal phosphate: Biosynthesis and catabolism

(2011) Tathagata Mukherjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Porphyromonas gingivalis SerB-mediated dephosphorylation of host cell cofilin modulates invasion efficiency

(2011) Catherine E. Moffatt et al.   CELLULAR MICROBIOLOGY

Mining high-throughput experimental data to link gene and function

(2011) Crysten E. Blaby-Haas et al.   TRENDS IN BIOTECHNOLOGY

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

HDHD1, which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5′-phosphatase

(2010) Alice Preumont et al.   BIOCHEMICAL JOURNAL

A mitochondrial phosphatase required for cardiolipin biosynthesis: the PGP phosphatase Gep4

(2010) Christof Osman et al.   EMBO JOURNAL

Structure and Activity of the Metal-independent Fructose-1,6-bisphosphatase YK23 fromSaccharomyces cerevisiae

(2010) Ekaterina Kuznetsova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The RNA modification database, RNAMDB: 2011 update

(2010) W. A. Cantara et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of the pyrimidine 5′-nucleotidase SDT1 from Saccharomyces cerevisiae complexed with uridine 5′-monophosphate provides further insight into ligand binding

(2010) Nuo Shi et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Global Protein Kinase and Phosphatase Interaction Network in Yeast

(2010) A. Breitkreutz et al.   SCIENCE

From complete genome sequence to ‘complete’ understanding?

(2010) Michael Y. Galperin et al.   TRENDS IN BIOTECHNOLOGY

The Structural and Biochemical Foundations of Thiamin Biosynthesis

(2009) Christopher T. Jurgenson et al.   Annual Review of Biochemistry

‘Unknown’ proteins and ‘orphan’ enzymes: the missing half of the engineering parts list – and how to find it

(2009) Andrew D. Hanson et al.   BIOCHEMICAL JOURNAL

Markers of fitness in a successful enzyme superfamily

(2009) Karen N Allen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Identification of Isn1 and Sdt1 as Glucose- and Vitamin-regulated Nicotinamide Mononucleotide and Nicotinic Acid Mononucleotide 5′-Nucleotidases Responsible for Production of Nicotinamide Riboside and Nicotinic Acid Riboside

(2009) Katrina L. Bogan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1

(2009) K. Takeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Annotation Error in Public Databases: Misannotation of Molecular Function in Enzyme Superfamilies

(2009) Alexandra M. Schnoes et al.   PLoS Computational Biology

Identification and Characterization of a Bacterial Glycerol-1-phosphate Dehydrogenase: Ni2+-Dependent AraM fromBacillus subtilis†

(2008) Harald Guldan et al.   BIOCHEMISTRY

TheSaccharomyces cerevisiae PHM8Gene Encodes a Soluble Magnesium-dependent Lysophosphatidic Acid Phosphatase

(2008) Venky Sreedhar Reddy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Identification of Pseudouridine-metabolizing Enzymes

(2008) Alice Preumont et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deleting the para-nitrophenyl phosphatase (pNPPase), PHO13, in recombinant Saccharomyces cerevisiae improves growth and ethanol production on d-xylose

(2008) Jennifer Headman Van Vleet et al.   METABOLIC ENGINEERING