The Evolutionarily Conserved Tre2/Bub2/Cdc16 (TBC), Lysin Motif (LysM), Domain Catalytic (TLDc) Domain Is Neuroprotective against Oxidative Stress

Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity

(2016) Manlio Vinciguerra et al.   Aging-US

Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis

(2015) Kevin X. Liu et al.   BRAIN

Homozygous TBC1D24 mutation in two siblings with familial infantile myoclonic epilepsy (FIME) and moderate intellectual disability

(2015) Anne-Lise Poulat et al.   EPILEPSY RESEARCH

Early-onset epileptic encephalopathy with hearing loss in two siblings with TBC1D24 recessive mutations

(2015) Barbara Gnidovec Stražišar et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

AlacZreporter gene expression atlas for 313 adult KOMP mutant mouse lines

(2015) David B. West et al.   GENOME RESEARCH

Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations

(2015) M. J. Finelli et al.   HUMAN MOLECULAR GENETICS

Induction of a Unique Isoform of theNCOA7Oxidation Resistance Gene by Interferon β-1b

(2015) Lijian Yu et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

A Novel HomozygousTBC1D24Mutation Causing Multifocal Myoclonus With Cerebellar Involvement

(2015) Diane Doummar et al.   MOVEMENT DISORDERS

Transcriptional profiling of macrophages derived from monocytes and iPS cells identifies a conserved response to LPS and novel alternative transcription

(2015) Kaur Alasoo et al.   Scientific Reports

Mutations in TBC1D24, a Gene Associated With Epilepsy, Also Cause Nonsyndromic Deafness DFNB86

(2014) Atteeq U. Rehman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21

(2014) Mingyi Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidation resistance 1 is essential for protection against oxidative stress and participates in the regulation of aging inCaenorhabditis elegans

(2014) Y. Sanada et al.   FREE RADICAL RESEARCH

TBC1D24Mutation Causes Autosomal-Dominant Nonsyndromic Hearing Loss

(2014) Hela Azaiez et al.   HUMAN MUTATION

Reduced synaptic vesicle protein degradation at lysosomes curbsTBC1D24/sky-induced neurodegeneration

(2014) Ana Clara Fernandes et al.   JOURNAL OF CELL BIOLOGY

Cloning of cDNA encoding a Bombyx mori homolog of human oxidation resistance 1 (OXR1) protein from diapause eggs, and analyses of its expression and function

(2014) Noriko Kobayashi et al.   JOURNAL OF INSECT PHYSIOLOGY

TBC1D24 regulates neuronal migration and maturation through modulation of the ARF6-dependent pathway

(2014) Antonio Falace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TBC1D24 mutation associated with focal epilepsy, cognitive impairment and a distinctive cerebro-cerebellar malformation

(2013) Zaid Afawi et al.   EPILEPSY RESEARCH

Novel Compound Heterozygous Mutations inTBC1D24Cause Familial Malignant Migrating Partial Seizures of Infancy

(2013) Mathieu Milh et al.   HUMAN MUTATION

TBC1D24truncating mutation resulting in severe neurodegeneration

(2013) Ayse Guven et al.   JOURNAL OF MEDICAL GENETICS

The genetic basis of DOORS syndrome: an exome-sequencing study

(2013) Philippe M Campeau et al.   LANCET NEUROLOGY

Structural/functional analysis of the human OXR1 protein: identification of exon 8 as the anti-oxidant encoding function

(2012) Kenan C Murphy et al.   BMC MOLECULAR BIOLOGY

The Drosophila Protein Mustard Tailors the Innate Immune Response Activated by the Immune Deficiency Pathway

(2012) Z. Wang et al.   JOURNAL OF IMMUNOLOGY

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

Crystal structure of the TLDc domain of oxidation resistance protein 2 from zebrafish

(2012) Mickaël Blaise et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Loss of Skywalker Reveals Synaptic Endosomes as Sorting Stations for Synaptic Vesicle Proteins

(2011) Valerie Uytterhoeven et al.   CELL

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Oxidative Stress in Neurodegenerative Diseases: Mechanisms and Therapeutic Perspectives

(2011) Ailton Melo et al.   Oxidative Medicine and Cellular Longevity

Oxr1 Is Essential for Protection against Oxidative Stress-Induced Neurodegeneration

(2011) Peter L. Oliver et al.   PLoS Genetics

A Focal Epilepsy and Intellectual Disability Syndrome Is Due to a Mutation in TBC1D24

(2010) Mark A. Corbett et al.   AMERICAN JOURNAL OF HUMAN GENETICS

TBC1D24, an ARF6-Interacting Protein, Is Mutated in Familial Infantile Myoclonic Epilepsy

(2010) Antonio Falace et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Anopheles gambiae Oxidation Resistance 1 (OXR1) Gene Regulates Expression of Enzymes That Detoxify Reactive Oxygen Species

(2010) Giovanna Jaramillo-Gutierrez et al.   PLoS One

Long noncoding RNA genes: conservation of sequence and brain expression among diverse amniotes

(2010) Rebecca A Chodroff et al.   GENOME BIOLOGY

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Neuronal gene expression correlates of Parkinson's disease with dementia

(2008) Chelsea Stamper et al.   MOVEMENT DISORDERS

Molecular characterization and bioinformatics analysis of Ncoa7B, a novel ovulation-associated and reproduction system-specific Ncoa7 isoform

(2008) Ketty Shkolnik et al.   REPRODUCTION