Partially Unfolded Forms of the Prion Protein Populated under Misfolding-promoting Conditions

Structural Effects of Multiple Pathogenic Mutations Suggest a Model for the Initiation of Misfolding of the Prion Protein

(2015) Jogender Singh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Native-like Intermediate Serves as a Branching Point between the Folding and Aggregation Pathways of the Mouse Prion Protein

(2015) Ryo P. Honda et al.   STRUCTURE

Thermodynamic Characterization of the Unfolding of the Prion Protein

(2014) Roumita Moulick et al.   BIOPHYSICAL JOURNAL

Acid-induced Molten Globule State of a Prion Protein

(2014) Ryo P. Honda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rational Stabilization of Helix 2 of the Prion Protein Prevents Its Misfolding and Oligomerization

(2014) Jogender Singh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of the Structural Core and of Conformational Heterogeneity during the Conversion of Oligomers of the Mouse Prion Protein to Worm-like Amyloid Fibrils

(2012) Jogender Singh et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein hydrogen exchange: Testing current models

(2012) John J. Skinner et al.   PROTEIN SCIENCE

Microsecond Unfolding Kinetics of Sheep Prion Protein Reveals an Intermediate that Correlates with Susceptibility to Classical Scrapie

(2011) Kai-Chun Chen et al.   BIOPHYSICAL JOURNAL

Detailed Biophysical Characterization of the Acid-Induced PrPcto PrPβConversion Process

(2010) Trent C. Bjorndahl et al.   BIOCHEMISTRY

Local Cooperativity in an Amyloidogenic State of Human Lysozyme Observed at Atomic Resolution

(2010) Anne Dhulesia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prion disease susceptibility is affected by  -structure folding propensity and local side-chain interactions in PrP

(2010) M. Q. Khan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prion hypothesis: the end of the controversy?

(2010) Claudio Soto   TRENDS IN BIOCHEMICAL SCIENCES

Prion Proteins with Pathogenic and Protective Mutations Show Similar Structure and Dynamics

(2009) Sung-Hun Bae et al.   BIOCHEMISTRY

Folding kinetics of the human prion protein probed by temperature jump

(2009) T. Hart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helical structure and stability in human apolipoprotein A-I by hydrogen exchange and mass spectrometry

(2009) Palaniappan Sevugan Chetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States

(2008) Natallia Makarava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Stepwise Formation of Amyloid Fibrils by the Mouse Prion Protein

(2008) Shweta Jain et al.   JOURNAL OF MOLECULAR BIOLOGY

Amyloid formation by globular proteins under native conditions

(2008) Fabrizio Chiti et al.   Nature Chemical Biology

Conformational pH dependence of intermediate states during oligomerization of the human prion protein

(2008) Remo Gerber et al.   PROTEIN SCIENCE