Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia

The Q loops of the human multidrug resistance transporter ABCB1 are necessary to couple drug binding to the ATP catalytic cycle

(2014) Joseph K. Zolnerciks et al.   FASEB JOURNAL

CFTR structure and cystic fibrosis

(2014) Natasha Cant et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ATP and AMP Mutually Influence Their Interaction with the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) at Separate Binding Sites

(2013) Christoph O. Randak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CFTR Ion Channel: Gating, Regulation, and Anion Permeation

(2013) T.-C. Hwang et al.   Cold Spring Harbor Perspectives in Medicine

Demonstration of Phosphoryl Group Transfer Indicates That the ATP-binding Cassette (ABC) Transporter Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Exhibits Adenylate Kinase Activity

(2012) Christoph O. Randak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor

(2011) Runying Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Human-mouse cystic fibrosis transmembrane conductance regulator (CFTR) chimeras identify regions that partially rescue CFTR- F508 processing and alter its gating defect

(2011) Q. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Snapshots of the maltose transporter during ATP hydrolysis

(2011) M. L. Oldham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies

(2011) Christina E. Drakou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia

(2010) Jeng-Haur Chen et al.   CELL

Structural Basis for Adenylate Kinase Activity in ABC ATPases

(2010) Alfred Lammens et al.   JOURNAL OF MOLECULAR BIOLOGY

Gating of the CFTR Cl−channel by ATP-driven nucleotide-binding domain dimerisation

(2009) Tzyh-Chang Hwang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Molecular basis for the ATPase activity of CFTR

(2008) Joanne C. Cheung et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A Mutation in CFTR Modifies the Effects of the Adenylate Kinase Inhibitor Ap5A on Channel Gating

(2008) Qian Dong et al.   BIOPHYSICAL JOURNAL

Structure, Function, and Evolution of Bacterial ATP-Binding Cassette Systems

(2008) A. L. Davidson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS