Attenuation of the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway byPorphyromonas gingivalisGingipains RgpA, RgpB, and Kgp

Porphyromonas gingivalis-induced autophagy suppresses cell proliferation through G1 arrest in oral cancer cells

(2014) Tae Jin Cho et al.   ARCHIVES OF ORAL BIOLOGY

Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway

(2014) C-H Lee et al.   GENE THERAPY

Oral Porphyromonas gingivalis translocates to the liver and regulates hepatic glycogen synthesis through the Akt/GSK-3β signaling pathway

(2013) Makoto Ishikawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hemoglobin Receptor Protein from Porphyromonas gingivalis Induces Interleukin-8 Production in Human Gingival Epithelial Cells through Stimulation of the Mitogen-Activated Protein Kinase and NF-κB Signal Transduction Pathways

(2013) Yuki Fujita et al.   INFECTION AND IMMUNITY

Involvement of phosphatidylinositol 3-Kinase/Akt signaling pathway in β1 integrin-mediated internalization of Staphylococcus aureus by alveolar epithelial cells

(2013) Jia-He Wang et al.   JOURNAL OF MICROBIOLOGY

Effect of Porphyromonas gingivalis outer membrane vesicles on gingipain-mediated detachment of cultured oral epithelial cells and immune responses

(2013) Ryoma Nakao et al.   MICROBES AND INFECTION

Gingipain-dependent degradation of mammalian target of rapamycin pathway proteins by the periodontal pathogenPorphyromonas gingivalisduring invasion

(2013) P. Stafford et al.   Molecular Oral Microbiology

Porphyromonas gingivalis influences actin degradation within epithelial cells during invasion and apoptosis

(2012) James A. Kinane et al.   CELLULAR MICROBIOLOGY

Porphyromonas gingivalis lipopolysaccharide regulates interleukin (IL)-17 and IL-23 expression via SIRT1 modulation in human periodontal ligament cells

(2012) Yong-Duk Park et al.   CYTOKINE

Identification of Signaling Pathways Mediating Cell Cycle Arrest and Apoptosis Induced by Porphyromonas gingivalis in Human Trophoblasts

(2012) Hiroaki Inaba et al.   INFECTION AND IMMUNITY

Proteasome-dependent Activation of Mammalian Target of Rapamycin Complex 1 (mTORC1) Is Essential for Autophagy Suppression and Muscle Remodeling Following Denervation

(2012) Pham Nguyen Quy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Porphyromonas gingivalis entry into gingival epithelial cells modulated by Fusobacterium nucleatum is dependent on lipid rafts

(2012) Atsushi Saito et al.   MICROBIAL PATHOGENESIS

Luteolin and fisetin inhibit the effects of lipopolysaccharide obtained from Porphyromonas gingivalis in human gingival fibroblasts

(2012) Gloria Gutiérrez-Venegas et al.   MOLECULAR BIOLOGY REPORTS

TORC1 Regulates Endocytosis via Npr1-Mediated Phosphoinhibition of a Ubiquitin Ligase Adaptor

(2011) Jason A. MacGurn et al.   CELL

Porphyromonas gingivalis SerB-mediated dephosphorylation of host cell cofilin modulates invasion efficiency

(2011) Catherine E. Moffatt et al.   CELLULAR MICROBIOLOGY

Regulation of TFEB and V-ATPases by mTORC1

(2011) Samuel Peña-Llopis et al.   EMBO JOURNAL

Schisandra chinensis α-iso-cubebenol induces heme oxygenase-1 expression through PI3K/Akt and Nrf2 signaling and has anti-inflammatory activity in Porphyromonas gingivalis lipopolysaccharide-stimulated macrophages

(2011) Sun Young Park et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Diabetes mellitus and periodontitis: a tale of two common interrelated diseases

(2011) Evanthia Lalla et al.   Nature Reviews Endocrinology

Regulation of Akt signaling activation by ubiquitination

(2010) Wei-Lei Yang et al.   CELL CYCLE

Role of Porphyromonas gingivalis Phosphoserine Phosphatase Enzyme SerB in Inflammation, Immune Response, and Induction of Alveolar Bone Resorption in Rats

(2010) B. Bainbridge et al.   INFECTION AND IMMUNITY

Porphyromonas gingivalisinfection sequesters pro-apoptotic Bad through Akt in primary gingival epithelial cells

(2010) L. Yao et al.   Molecular Oral Microbiology

The PKB/AKT Pathway in Cancer

(2009) Amancio Carnero   CURRENT PHARMACEUTICAL DESIGN

The gingipains: scissors and glue of the periodontal pathogen,Porphyromonas gingivalis

(2009) Rebecca E Fitzpatrick et al.   Future Microbiology

Entry of Porphyromonas gingivalis Outer Membrane Vesicles into Epithelial Cells Causes Cellular Functional Impairment

(2009) N. Furuta et al.   INFECTION AND IMMUNITY

Porphyromonas gingivalis Outer Membrane Vesicles Enter Human Epithelial Cells via an Endocytic Pathway and Are Sorted to Lysosomal Compartments

(2009) N. Furuta et al.   INFECTION AND IMMUNITY

Cdc42 and the Phosphatidylinositol 3-Kinase-Akt Pathway Are Essential for PspC-mediated Internalization of Pneumococci by Respiratory Epithelial Cells

(2009) Vaibhav Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Induction of Distinct TLR2-Mediated Proinflammatory and Proadhesive Signaling Pathways in Response to Porphyromonas gingivalis Fimbriae

(2009) G. Hajishengallis et al.   JOURNAL OF IMMUNOLOGY

Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses

(2009) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcineurin mediates AKT dephosphorylation in the ischemic rat retina

(2008) Chang Hwan Park et al.   BRAIN RESEARCH

Functional Analysis of α5β1 Integrin and Lipid Rafts in Invasion of Epithelial Cells by Porphyromonas gingivalis using Fluorescent Beads Coated with Bacterial Membrane Vesicles

(2008) Kayoko Tsuda et al.   CELL STRUCTURE AND FUNCTION

Stimulation of Toll-Like Receptor 2 in Human Platelets Induces a Thromboinflammatory Response Through Activation of Phosphoinositide 3-Kinase

(2008) Price Blair et al.   CIRCULATION RESEARCH

Helicobacter pyloriVacA-induced Inhibition of GSK3 through the PI3K/Akt Signaling Pathway

(2008) Masaaki Nakayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin Resistance

(2008) J. R. Bayascas et al.   MOLECULAR AND CELLULAR BIOLOGY

Inactivation of Host Akt/Protein Kinase B Signaling by Bacterial Pore-forming Toxins

(2008) Travis J. Wiles et al.   MOLECULAR BIOLOGY OF THE CELL