Subcellular Localization and Ser-137 Phosphorylation Regulate Tumor-suppressive Activity of Profilin-1

Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1α axis

(2014) Wantong Yao et al.   Molecular Cancer

Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation

(2014) Yi Fan et al.   NATURE CELL BIOLOGY

A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells

(2013) J. R. Stehn et al.   CANCER RESEARCH

Profilin1 Sensitizes Pancreatic Cancer Cells to Irradiation by Inducing Apoptosis and Reducing Autophagy

(2013) H. Cheng et al.   CURRENT MOLECULAR MEDICINE

Stimulus-dependent phosphorylation of profilin-1 in angiogenesis

(2012) Yi Fan et al.   NATURE CELL BIOLOGY

Profilin is associated with transcriptionally active genes

(2012) Emilia Söderberg et al.   Nucleus

Profilin1 facilitates staurosporine-triggered apoptosis by stabilizing the integrin β1-actin complex in breast cancer cells

(2011) Wantong Yao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Profilin 1 is a Potential Biomarker for Bladder Cancer Aggressiveness

(2011) Jerome Zoidakis et al.   MOLECULAR & CELLULAR PROTEOMICS

A Multifunctional Lentiviral-Based Gene Knockdown with Concurrent Rescue that Controls for Off-Target Effects of RNAi

(2011) Yunfeng Feng et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Depletion of nuclear actin is a key mediator of quiescence in epithelial cells

(2010) V. A. Spencer et al.   JOURNAL OF CELL SCIENCE

Profilin 1 is required for abscission during late cytokinesis of chondrocytes

(2009) Ralph T Böttcher et al.   EMBO JOURNAL

Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression

(2009) Bin Zheng et al.   FEBS Journal

Loss of profilin-1 expression enhances breast cancer cell motility by Ena/VASP proteins

(2009) Yong Ho Bae et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mutational Analysis Reveals a Noncontractile but Interactive Role of Actin and Profilin in Viral RNA-Dependent RNA Synthesis

(2009) M. Harpen et al.   JOURNAL OF VIROLOGY

Profilin, a multi-modal regulator of neuronal plasticity

(2008) Andreas Birbach   BIOESSAYS

Phosphorylation of Profilin by ROCK1 Regulates Polyglutamine Aggregation

(2008) J. Shao et al.   MOLECULAR AND CELLULAR BIOLOGY