Conformational Changes in the Endosomal Sorting Complex Required for the Transport III Subunit Ist1 Lead to Distinct Modes of ATPase Vps4 Regulation

Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains

(2015) Emily Z. Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs)

(2015) Han Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

(2015) Marina Vietri et al.   NATURE

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation

(2015) Bei Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stochastic but Highly Coordinated Protein Unfolding and Translocation by the ClpXP Proteolytic Machine

(2014) Juan Carlos Cordova et al.   CELL

Vps4 Stimulatory Element of the Cofactor Vta1 Contacts the ATPase Vps4 α7 and α9 to Stimulate ATP Hydrolysis

(2014) Brian A. Davies et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of cellular ESCRT-III spirals and their relationship to HIV budding

(2014) Anil G Cashikar et al.   eLife

Membrane Fission Reactions of the Mammalian ESCRT Pathway

(2013) John McCullough et al.   Annual Review of Biochemistry

ClpX Shifts into High Gear to Unfold Stable Proteins

(2013) Michael R. Maurizi et al.   CELL

The Linker Region Plays a Regulatory Role in Assembly and Activity of the Vps4 AAA ATPase

(2013) Anna Shestakova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relief of Autoinhibition Enhances Vta1 Activation of Vps4 via the Vps4 Stimulatory Element

(2013) Andrew P. Norgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An ESCRT–spastin interaction promotes fission of recycling tubules from the endosome

(2013) Rachel Allison et al.   JOURNAL OF CELL BIOLOGY

The Oligomeric State of the Active Vps4 AAA ATPase

(2013) Nicole Monroe et al.   JOURNAL OF MOLECULAR BIOLOGY

The AAA ATPase spastin links microtubule severing to membrane modelling

(2011) Jennifer H. Lumb et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ClpXP, an ATP-powered unfolding and protein-degradation machine

(2011) Tania A. Baker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ESCRT-III Protein Requirements for HIV-1 Budding

(2011) Eiji Morita et al.   Cell Host & Microbe

Assembly and disassembly of the ESCRT-III membrane scission complex

(2011) Manuel Alonso Y Adell et al.   FEBS LETTERS

A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination

(2011) Daniel K. Stringer et al.   JOURNAL OF CELL BIOLOGY

Cortical Constriction During Abscission Involves Helices of ESCRT-III-Dependent Filaments

(2011) J. Guizetti et al.   SCIENCE

Regulation of Membrane Protein Degradation by Starvation-Response Pathways

(2011) Charles B. Jones et al.   TRAFFIC

Activation of Human VPS4A by ESCRT-III Proteins Reveals Ability of Substrates to Relieve Enzyme Autoinhibition

(2010) Samuel A. Merrill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SPG20 Protein Spartin Is Recruited to Midbodies by ESCRT-III Protein Ist1 and Participates in Cytokinesis

(2010) Benoît Renvoisé et al.   MOLECULAR BIOLOGY OF THE CELL

Coordination of Substrate Binding and ATP Hydrolysis in Vps4-Mediated ESCRT-III Disassembly

(2010) Brian A. Davies et al.   MOLECULAR BIOLOGY OF THE CELL

Regulators of Vps4 ATPase Activity at Endosomes Differentially Influence the Size and Rate of Formation of Intralumenal Vesicles

(2010) Daniel P. Nickerson et al.   MOLECULAR BIOLOGY OF THE CELL

Assembly of the AAA ATPase Vps4 on ESCRT-III

(2010) Anna Shestakova et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular mechanism of multivesicular body biogenesis by ESCRT complexes

(2010) Thomas Wollert et al.   NATURE

Functional Reconstitution of ESCRT-III Assembly and Disassembly

(2009) Suraj Saksena et al.   CELL

Structure and Function of the ESCRT-II-III Interface in Multivesicular Body Biogenesis

(2009) Young Jun Im et al.   DEVELOPMENTAL CELL

Biochemical Analyses of Human IST1 and Its Function in Cytokinesis

(2009) Monika Bajorek et al.   MOLECULAR BIOLOGY OF THE CELL

Essential Role of hIST1 in Cytokinesis

(2009) Monica Agromayor et al.   MOLECULAR BIOLOGY OF THE CELL

Structural Basis of Ist1 Function and Ist1–Did2 Interaction in the Multivesicular Body Pathway and Cytokinesis

(2009) Junyu Xiao et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane scission by the ESCRT-III complex

(2009) Thomas Wollert et al.   NATURE

Structural basis for ESCRT-III protein autoinhibition

(2009) Monika Bajorek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Three-Dimensional Structure of AAA ATPase Vps4: Advancing Structural Insights into the Mechanisms of Endosomal Sorting and Enveloped Virus Budding

(2009) Michael John Landsberg et al.   STRUCTURE

Computational Model of Membrane Fission Catalyzed by ESCRT-III

(2009) Gur Fabrikant et al.   PLoS Computational Biology

ESCRT-III Family Members Stimulate Vps4 ATPase Activity Directly or via Vta1

(2008) Ishara F. Azmi et al.   DEVELOPMENTAL CELL

Ordered Assembly of the ESCRT-III Complex on Endosomes Is Required to Sequester Cargo during MVB Formation

(2008) David Teis et al.   DEVELOPMENTAL CELL

MIT Domainia

(2008) James H. Hurley et al.   DEVELOPMENTAL CELL

Two Distinct Modes of ESCRT-III Recognition Are Required for VPS4 Functions in Lysosomal Protein Targeting and HIV-1 Budding

(2008) Collin Kieffer et al.   DEVELOPMENTAL CELL

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

(2008) Phyllis I. Hanson et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for Autoinhibition of ESCRT-III CHMP3

(2008) Suman Lata et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural basis for midbody targeting of spastin by the ESCRT-III protein CHMP1B

(2008) Dong Yang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding

(2008) Andreas Martin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Differential requirements for Alix and ESCRT-III in cytokinesis and HIV-1 release

(2008) J. G. Carlton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Ist1-Did2 Complex Functions at a Late Step in Multivesicular Body Sorting

(2007) Sarah M. Rue et al.   MOLECULAR BIOLOGY OF THE CELL

Ist1 Regulates Vps4 Localization and Assembly

(2007) Christian Dimaano et al.   MOLECULAR BIOLOGY OF THE CELL