Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid

Tau acts as a mediator for Alzheimer's disease-related synaptic deficits

(2014) Dezhi Liao et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

(2014) Shichun Tu et al.   Molecular Neurodegeneration

c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo

(2014) A Sclip et al.   Cell Death & Disease

Impact of Sustained Exposure to β-Amyloid on Calcium Homeostasis and Neuronal Integrity in Model Nerve Cell System Expressing α4β2 Nicotinic Acetylcholine Receptors

(2013) Komal Arora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Role of Key Aromatic Residues in the Ligand-binding Domain of α7 Nicotinic Receptors in the Agonist Action of β-Amyloid

(2011) Mei Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Loss of c-Jun N-Terminal Protein Kinase Activity Prevents the Amyloidogenic Cleavage of Amyloid Precursor Protein and the Formation of Amyloid Plaques In Vivo

(2011) S. Mazzitelli et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Inhibition of JNK phosphorylation reverses memory deficit induced by β-amyloid (1–42) associated with decrease of apoptotic factors

(2010) Mahmoudreza Ramin et al.   BEHAVIOURAL BRAIN RESEARCH

α7 nAChR-mediated activation of MAP kinase pathways in PC12 cells

(2010) Earl J. Gubbins et al.   BRAIN RESEARCH

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Fyn-Tau-Amyloid: A Toxic Triad

(2010) Christian Haass et al.   CELL

β-Amyloid activates presynaptic α7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts

(2010) Ghous M. Khan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Hippocampal c-Jun-N-Terminal Kinases Serve as Negative Regulators of Associative Learning

(2010) T. Sherrin et al.   JOURNAL OF NEUROSCIENCE

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Loss of  7 Nicotinic Receptors Enhances  -Amyloid Oligomer Accumulation, Exacerbating Early-Stage Cognitive Decline and Septohippocampal Pathology in a Mouse Model of Alzheimer's Disease

(2010) C. M. Hernandez et al.   JOURNAL OF NEUROSCIENCE

Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease

(2010) Steven P. Braithwaite et al.   NEUROBIOLOGY OF DISEASE

Cognitive Improvement by Activation of α7 Nicotinic Acetylcholine Receptors: From Animal Models to Human Pathophysiology

(2009) Morten Thomsen et al.   CURRENT PHARMACEUTICAL DESIGN

Pharmacology of the Intracellular Pathways Activated by Amyloid Beta Protein

(2009) Hugo Balleza-Tapia et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Nicotine-induced phosphorylation of extracellular signal-regulated protein kinase and CREB in PC12h cells

(2003) Hitoshi Nakayama et al.   JOURNAL OF NEUROCHEMISTRY