Identification of a Novel HIV-1 Inhibitor Targeting Vif-dependent Degradation of Human APOBEC3G Protein
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Title
Identification of a Novel HIV-1 Inhibitor Targeting Vif-dependent Degradation of Human APOBEC3G Protein
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 290, Issue 16, Pages 10504-10517
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2015-02-28
DOI
10.1074/jbc.m114.626903
References
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Related references
Note: Only part of the references are listed.- Structure-Guided Analysis of the Human APOBEC3-HIV Restrictome
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- Interactions between HIV-1 Vif and human ElonginB-ElonginC are important for CBF-β binding to Vif
- (2013) Xiaodan Wang et al. Retrovirology
- Crystal Structure of the DNA Cytosine Deaminase APOBEC3F: The Catalytically Active and HIV-1 Vif-Binding Domain
- (2013) Markus-Frederik Bohn et al. STRUCTURE
- Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F
- (2013) Karen K. Siu et al. Nature Communications
- The Ability of Primate Lentiviruses to Degrade the Monocyte Restriction Factor SAMHD1 Preceded the Birth of the Viral Accessory Protein Vpx
- (2012) Efrem S. Lim et al. Cell Host & Microbe
- APOBEC3G Restricts HIV-1 to a Greater Extent than APOBEC3F and APOBEC3DE in Human Primary CD4+ T Cells and Macrophages
- (2012) C. Chaipan et al. JOURNAL OF VIROLOGY
- Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Replication by Targeting the Interaction between Vif and ElonginC
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- Suppression of HIV-1 Infection by APOBEC3 Proteins in Primary Human CD4+T Cells Is Associated with Inhibition of Processive Reverse Transcription as Well as Excessive Cytidine Deamination
- (2012) Kieran Gillick et al. JOURNAL OF VIROLOGY
- The APOBEC3C crystal structure and the interface for HIV-1 Vif binding
- (2012) Shingo Kitamura et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
- (2011) Stefanie Jäger et al. NATURE
- Small Molecular Compounds Inhibit HIV-1 Replication through Specifically Stabilizing APOBEC3G
- (2010) Shan Cen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of a Critical T(Q/D/E)x5ADx2(I/L) Motif from Primate Lentivirus Vif Proteins That Regulate APOBEC3G and APOBEC3F Neutralizing Activity
- (2010) Y. Dang et al. JOURNAL OF VIROLOGY
- Identification of 81LGxGxxIxW89 and 171EDRW174 Domains from Human Immunodeficiency Virus Type 1 Vif That Regulate APOBEC3G and APOBEC3F Neutralizing Activity
- (2010) Y. Dang et al. JOURNAL OF VIROLOGY
- Inhibition of Human Immunodeficiency Virus Type 1 Replication in Human Cells by Debio-025, a Novel Cyclophilin Binding Agent
- (2008) R. G. Ptak et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Regulation of APOBEC3 Proteins by a Novel YXXL Motif in Human Immunodeficiency Virus Type 1 Vif and Simian Immunodeficiency Virus SIVagm Vif
- (2008) E. Pery et al. JOURNAL OF VIROLOGY
- Structural Insight into the Human Immunodeficiency Virus Vif SOCS Box and Its Role in Human E3 Ubiquitin Ligase Assembly
- (2008) B. J. Stanley et al. JOURNAL OF VIROLOGY
- The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction
- (2008) A. J. Schumacher et al. JOURNAL OF VIROLOGY
- Identification of amino acid residues in HIV-1 Vif critical for binding and exclusion of APOBEC3G/F
- (2008) T YAMASHITA et al. MICROBES AND INFECTION
- Small-molecule inhibition of HIV-1 Vif
- (2008) Robin Nathans et al. NATURE BIOTECHNOLOGY
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