The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation

Genetic and functional characterization of clonally derived adult human brown adipocytes

(2015) Kosaku Shinoda et al.   NATURE MEDICINE

Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch

(2014) Paul Cohen et al.   CELL

A Smooth Muscle-Like Origin for Beige Adipocytes

(2014) Jonathan Z. Long et al.   Cell Metabolism

Inhibiting DNA Methylation by 5-Aza-2′-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation

(2014) Qiang Cao et al.   ENDOCRINOLOGY

Epigenetic Regulation of Macrophage Polarization by DNA Methyltransferase 3b

(2014) Xiaosong Yang et al.   MOLECULAR ENDOCRINOLOGY

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

(2014) Panagiotis Ntziachristos et al.   NATURE

Histone demethylase Jmjd3 is required for the development of subsets of retinal bipolar cells

(2014) A. Iida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H3K27me and PRC2 transmit a memory of repression across generations and during development

(2014) L. J. Gaydos et al.   SCIENCE

EBF2 Determines and Maintains Brown Adipocyte Identity

(2013) Sona Rajakumari et al.   Cell Metabolism

Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

(2013) P. W. Lewis et al.   SCIENCE

Epigenetic regulation of adipogenesis by histone methylation

(2012) Kai Ge   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

Energy Balance and Obesity

(2012) James O. Hill et al.   CIRCULATION

Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis

(2012) Lifeng Wang et al.   EMBO JOURNAL

Nature or nurture: Let food be your epigenetic medicine in chronic inflammatory disorders

(2010) Katarzyna Szarc vel Szic et al.   BIOCHEMICAL PHARMACOLOGY

Epigenome Mapping in Normal and Disease States

(2010) Alika K. Maunakea et al.   CIRCULATION RESEARCH

Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue

(2010) A. Shore et al.   DIABETOLOGIA

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Epigenetic regulation of development by histone lysine methylation

(2010) S Dambacher et al.   HEREDITY

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

(2010) Patrick Seale et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

(2010) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beige Can Be Slimming

(2010) J. Ishibashi et al.   SCIENCE

Epigenetic transgenerational actions of environmental factors in disease etiology

(2010) Michael K. Skinner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Epigenetics: A Molecular Link Between Environmental Factors and Type 2 Diabetes

(2009) Charlotte Ling et al.   DIABETES

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Individuality and epigenetics in obesity

(2009) J. Campión et al.   Obesity Reviews

Differential sympathetic drive to adipose tissues after food deprivation, cold exposure or glucoprivation

(2008) Nilton A. Brito et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation

(2008) Liselotte Bäckdahl et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE