The Nicotine Metabolite, Cotinine, Alters the Assembly and Trafficking of a Subset of Nicotinic Acetylcholine Receptors

Inside-out neuropharmacology of nicotinic drugs

(2015) Brandon J. Henderson et al.   NEUROPHARMACOLOGY

Selective Ligand Behaviors Provide New Insights into Agonist Activation of Nicotinic Acetylcholine Receptors

(2014) Christopher B. Marotta et al.   ACS Chemical Biology

α6β2*-subtype nicotinic acetylcholine receptors are more sensitive than α4β2*-subtype receptors to regulation by chronic nicotine administration

(2014) Michael J. Marks et al.   JOURNAL OF NEUROCHEMISTRY

Single-Particle Fluorescence Intensity Fluctuations of Carbon Nanodots

(2014) Somes K. Das et al.   NANO LETTERS

New Insights into the Mechanisms of Action of Cotinine and its Distinctive Effects from Nicotine

(2014) J. Alex Grizzell et al.   NEUROCHEMICAL RESEARCH

Pharmacological chaperoning of nAChRs: A therapeutic target for Parkinson's disease

(2014) Rahul Srinivasan et al.   PHARMACOLOGICAL RESEARCH

Biogenesis, trafficking and up-regulation of nicotinic ACh receptors

(2013) Sara Francesca Colombo et al.   BIOCHEMICAL PHARMACOLOGY

Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors

(2013) Brandon J. Henderson et al.   JOURNAL OF GENERAL PHYSIOLOGY

Nicotine-Modulated Subunit Stoichiometry Affects Stability and Trafficking of  3 4 Nicotinic Receptor

(2013) F. Mazzo et al.   JOURNAL OF NEUROSCIENCE

Cotinine: A Potential New Therapeutic Agent against Alzheimer's disease

(2012) Valentina Echeverria et al.   CNS Neuroscience & Therapeutics

Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2

(2012) Rahul Srinivasan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nicotine-Induced Upregulation of Native Neuronal Nicotinic Receptors Is Caused by Multiple Mechanisms

(2012) A. P. Govind et al.   JOURNAL OF NEUROSCIENCE

Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures

(2012) Christopher I. Richards et al.   NANO LETTERS

Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption

(2012) Valentina Echeverria Moran   Frontiers in Pharmacology

Additional Acetylcholine (ACh) Binding Site at α4/α4 Interface of (α4β2)2α4 Nicotinic Receptor Influences Agonist Sensitivity

(2011) Simone Mazzaferro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trafficking of α4* Nicotinic Receptors Revealed by Superecliptic Phluorin

(2011) Christopher I. Richards et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of chronic nicotine on heteromeric neuronal nicotinic receptors in rat primary cultured neurons

(2011) Ermelinda Lomazzo et al.   JOURNAL OF NEUROCHEMISTRY

Aversion to Nicotine Is Regulated by the Balanced Activity of β4 and α5 Nicotinic Receptor Subunits in the Medial Habenula

(2011) Silke Frahm et al.   NEURON

Neural Systems Governed by Nicotinic Acetylcholine Receptors: Emerging Hypotheses

(2011) Julie M. Miwa et al.   NEURON

Imaging with total internal reflection fluorescence microscopy for the cell biologist

(2010) A. L. Mattheyses et al.   JOURNAL OF CELL SCIENCE

Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning

(2010) Rahul Srinivasan et al.   JOURNAL OF GENERAL PHYSIOLOGY

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice

(2010) Jean-Pierre Changeux   NATURE REVIEWS NEUROSCIENCE

Parallel Anxiolytic-Like Effects and Upregulation of Neuronal Nicotinic Acetylcholine Receptors Following Chronic Nicotine and Varenicline

(2010) J. R. Turner et al.   NICOTINE & TOBACCO RESEARCH

Plasma membrane insertion of the AMPA receptor GluA2 subunit is regulated by NSF binding and Q/R editing of the ion pore

(2010) Y. Araki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry. Implications for Drug Discovery

(2009) Henry A. Lester et al.   AAPS Journal

Nicotine-induced upregulation of nicotinic receptors: Underlying mechanisms and relevance to nicotine addiction

(2009) Anitha P. Govind et al.   BIOCHEMICAL PHARMACOLOGY

Dynamic visualization of membrane-inserted fraction of pHluorin-tagged channels using repetitive acidification technique

(2009) Serguei S Khiroug et al.   BMC NEUROSCIENCE

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

(2009) Edson X. Albuquerque et al.   PHYSIOLOGICAL REVIEWS

Up-regulation of Nicotinic Receptors by Nicotine Varies with Receptor Subtype

(2008) Heather Walsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cotinine Selectively Activates a Subpopulation of  3/ 6 2 Nicotinic Receptors in Monkey Striatum

(2008) K. O'Leary et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Long-Term Nicotine Treatment Differentially Regulates Striatal  6 4 2* and  6(Non 4) 2* nAChR Expression and Function

(2008) X. A. Perez et al.   MOLECULAR PHARMACOLOGY