4.1 Article

Lipase-catalyzed transformations using poly(ethylene glycol) as solvent

Journal

BIOCATALYSIS AND BIOTRANSFORMATION
Volume 29, Issue 4, Pages 113-118

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/10242422.2011.578739

Keywords

Lipase; polyethylene glycol; heterogeneous catalyst; esterification; ammoniolysis; aminolysis

Funding

  1. University of Delhi

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Candida antarctica lipase catalyzes a number of elementary reactions like alcoholysis, ammoniolysis and aminolysis in poly(ethylene glycol) (PEG) media. Reaction rates were comparable to or better than those observed in conventional organic reaction media and ionic liquids. It is envisaged that PEGs could have added benefits for performing biotransformations with highly polar substrates, which are sparingly soluble in common organic solvents.

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