Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells

Nicotinamide Phosphoribosyl Transferase/Pre-B Cell Colony-Enhancing Factor/Visfatin Is Required for Lymphocyte Development and Cellular Resistance to Genotoxic Stress

(2014) A. Rongvaux et al.   JOURNAL OF IMMUNOLOGY

Fragment-Based Identification of Amides Derived from trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)

(2014) Anthony M. Giannetti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Basis for Regulation of Human Glucokinase by Glucokinase Regulatory Protein

(2013) Tobias Beck et al.   BIOCHEMISTRY

Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors

(2013) Xiaozhang Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+Biosynthesis, in Human Cancer Cells

(2012) Bo Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Riboneogenesis in Yeast

(2011) Michelle F. Clasquin et al.   CELL

Triosephosphate isomerase: a highly evolved biocatalyst

(2010) R. K. Wierenga et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Preclinical Study on the Rescue of Normal Tissue by Nicotinic Acid in High-Dose Treatment with APO866, a Specific Nicotinamide Phosphoribosyltransferase Inhibitor

(2010) U. H. Olesen et al.   MOLECULAR CANCER THERAPEUTICS

NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response

(2010) B Wang et al.   ONCOGENE

Niacin Status, NAD Distribution and ADP-Ribose Metabolism

(2009) James Kirkland   CURRENT PHARMACEUTICAL DESIGN

Nicotinamide Phosphoribosyltransferase (Nampt): A Link Between NAD Biology, Metabolism, and Diseases

(2009) Shin-ichiro Imai   CURRENT PHARMACEUTICAL DESIGN

Metabolic profiling reveals key metabolic features of renal cell carcinoma

(2009) Gareth Catchpole et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Adipocytokine levels in gastric cancer patients: resistin and visfatin as biomarkers of gastric cancer

(2009) Takako Eguchi Nakajima et al.   JOURNAL OF GASTROENTEROLOGY

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors

(2009) M. Watson et al.   MOLECULAR AND CELLULAR BIOLOGY

Anticancer agent CHS-828 inhibits cellular synthesis of NAD

(2008) Uffe Høgh Olesen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of mammalian sedoheptulokinase and mechanism of formation of erythritol in sedoheptulokinase deficiency

(2008) Tamas Kardon et al.   FEBS LETTERS

Pre-B cell colony-enhancing factor (PBEF)/visfatin: a novel mediator of innate immunity

(2008) T. Luk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase/Visfatin Enzymatic Activity Identifies a New Inflammatory Pathway Linked to NAD

(2008) Nathalie Busso et al.   PLoS One

Nampt: linking NAD biology, metabolism and cancer

(2008) Antje Garten et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM