Metabolomic Responses of Human Hepatocytes to Emodin, Aristolochic Acid, and Triptolide: Chemicals Purified from Traditional Chinese Medicines

A metabolomics study of the inhibitory effect of 17-beta-estradiol on osteoclast proliferation and differentiation

(2015) Xiaoyan Liu et al.   Molecular BioSystems

Serum acid sphingomyelinase is upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease

(2014) Georgios Grammatikos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Targeted liquid chromatography–mass spectrometry analysis of serum acylcarnitines in acetaminophen toxicity in children

(2014) Sudeepa Bhattacharyya et al.   Biomarkers in Medicine

Metabolite profiling and identification of triptolide in rats

(2013) Jia Liu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

An integrated metabonomics and transcriptomics approach to understanding metabolic pathway disturbance induced by perfluorooctanoic acid

(2013) Siyuan Peng et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Metabolomic profiling of sodium fluoride-induced cytotoxicity in an oral squamous cell carcinoma cell line

(2013) Hiroshi Sakagami et al.   Metabolomics

Autophagy induction promotes aristolochic acid-I-induced renal injury in vivo and in vitro

(2013) Ching-Chin Yang et al.   TOXICOLOGY

XCMS Online: A Web-Based Platform to Process Untargeted Metabolomic Data

(2012) Ralf Tautenhahn et al.   ANALYTICAL CHEMISTRY

Determination of emodin in L-02 cells and cell culture media with liquid chromatography–mass spectrometry: Application to a cellular toxicokinetic study

(2012) Cui-Li Li et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Sphingolipids as New Biomarkers for Assessment of Delayed-Type Hypersensitivity and Response to Triptolide

(2012) Feng Qu et al.   PLoS One

Time-Course Changes in Potential Biomarkers Detected Using a Metabonomic Approach in Walker 256 Tumor-Bearing Rats

(2011) Guoqing Shen et al.   JOURNAL OF PROTEOME RESEARCH

1H NMR-based metabolomic analysis of triptolide-induced toxicity in liver-specific cytochrome P450 reductase knockout mice

(2011) Xia Liu et al.   Metabolomics

Metabolomics Study of Stepwise Hepatocarcinogenesis From the Model Rats to Patients: Potential Biomarkers Effective for Small Hepatocellular Carcinoma Diagnosis

(2011) Yexiong Tan et al.   MOLECULAR & CELLULAR PROTEOMICS

Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry

(2011) Eric Chun Yong Chan et al.   Nature Protocols

Knockout of hepatic P450 reductase aggravates triptolide-induced toxicity

(2011) Xiang Xue et al.   TOXICOLOGY LETTERS

Metabolite extraction from adherently growing mammalian cells for metabolomics studies: optimization of harvesting and extraction protocols

(2010) Katja Dettmer et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Some common misunderstandings in chemometrics

(2010) Karin Kjeldahl et al.   JOURNAL OF CHEMOMETRICS

Sphingolipids in Multiple Sclerosis

(2010) Arundhati Jana et al.   NEUROMOLECULAR MEDICINE

Serum Metabolomics Reveals Irreversible Inhibition of Fatty Acid β-Oxidation through the Suppression of PPARα Activation as a Contributing Mechanism of Acetaminophen-Induced Hepatotoxicity

(2009) Chi Chen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Practical Approach for the Identification and Isomer Elucidation of Biomarkers Detected in a Metabonomic Study for the Discovery of Individuals at Risk for Diabetes by Integrating the Chromatographic and Mass Spectrometric Information

(2008) Jing Chen et al.   ANALYTICAL CHEMISTRY

Involvement of Mitochondrial Pathway in Triptolide-Induced Cytotoxicity in Human Normal Liver L-02 Cells

(2008) Jincheng Yao et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mass Spectrometry-Based Metabolic Profiling of Rat Urine Associated with General Toxicity Induced by the Multiglycoside ofTripterygium wilfordiiHook. f.

(2008) Minjun Chen et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease

(2008) Alfred H. Merrill et al.   JOURNAL OF LIPID RESEARCH

Assessment of PLSDA cross validation

(2008) Johan A. Westerhuis et al.   Metabolomics