Journal
BEHAVIOURAL PHARMACOLOGY
Volume 20, Issue 8, Pages 673-679Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/FBP.0b013e3283323c2a
Keywords
creatine ethyl ester; creatine monohydrate; human; intelligence; memory; oral supplementation; reaction time
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Supplementation with creatine-based substances as a means of enhancing athletic performance has become widespread. Until recently, however, the effects of creatine supplementation on cognitive performance has been given little attention. This study used a new form of creatine - creatine ethyl ester - to investigate whether supplementation would improve performance in five cognitive tasks, using a double-blind, placebo-controlled study. Creatine dosing led to an improvement over the placebo condition on several measures. Although creatine seems to facilitate cognition on some tasks, these results require replication using objective measures of compliance. The improvement is discussed in the context of research examining the influence of brain energy capacity on cognitive performance. Behavioural Pharmacology 20:673-679 (C) 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.
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