The Contribution of the Functional IL6R Polymorphism rs2228145, eQTLs and Other Genome-Wide SNPs to the Heritability of Plasma sIL-6R Levels

Sex differences in the human peripheral blood transcriptome

(2014) Rick Jansen et al.   BMC GENOMICS

A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk

(2013) J A Revez et al.   GENES AND IMMUNITY

Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression

(2013) Lorenzo de la Rica et al.   JOURNAL OF AUTOIMMUNITY

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

(2013) Ricardo C. Ferreira et al.   PLoS Genetics

Identification of cis-regulatory variation influencing protein abundance levels in human plasma

(2012) Anbarasu Lourdusamy et al.   HUMAN MOLECULAR GENETICS

MicroRNA-125b Functions as a Tumor Suppressor in Hepatocellular Carcinoma Cells

(2012) Hong-Yan Jia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

(2012)   LANCET

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

(2012)   LANCET

High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

(2012) Steve Eyre et al.   NATURE GENETICS

MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R

(2012) J Gong et al.   ONCOGENE

An intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification

(2011) O. W. Stephens et al.   BLOOD

An HNF4α-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis

(2011) Maria Hatziapostolou et al.   CELL

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

(2011) Manuel AR Ferreira et al.   LANCET

Genome partitioning of genetic variation for complex traits using common SNPs

(2011) Jian Yang et al.   NATURE GENETICS

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

(2011) Rudolf S. N. Fehrmann et al.   PLoS Genetics

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Heritability of Renal Function and Inflammatory Markers in Adult Male Twins

(2010) Paolo Raggi et al.   AMERICAN JOURNAL OF NEPHROLOGY

MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor

(2010) Li-Hua Zhu et al.   FEBS Journal

Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation

(2010) Shigeru Kotake et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies

(2010) Gonneke Willemsen et al.   Twin Research and Human Genetics

Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects

(2008) Dorret I Boomsma et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Identification of common genetic variants that account for transcript isoform variation between human populations

(2008) Wei Zhang et al.   HUMAN GENETICS

The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods

(2008) Brenda W.J.H. Penninx et al.   INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH

Genome-wide analysis of transcript isoform variation in humans

(2008) Tony Kwan et al.   NATURE GENETICS

A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)

(2008) David Melzer et al.   PLoS Genetics