Journal
BANGLADESH JOURNAL OF PHARMACOLOGY
Volume 6, Issue 1, Pages 51-54Publisher
BANGLADESH PHARMACOLOGICAL SOC
DOI: 10.3329/bjp.v6i1.8442
Keywords
Antileishmanial; Antimalarial; Carum copticum; Vincetoxicum stocksii
Categories
Funding
- Higher Education Commission of Pakistan
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The antileishmanial and antimalarial activities of different fractions of Vincetoxicum stocksii, Carum copticum, Gentiana olivierii and Zygophyllum fabago were determined. Amongst these, V. stocksii and C. copticum showed moderate to good antimalarial activity. The ethyl acetate fractions of C. copticum and hexane fraction of V. stocksii showed 94 % and 52% inhibition of Plasmodium falciparum (D6 Clone) respectively. The hexane ethyl acetate fraction of C. copticum V. stocksi exhibited antileishmanial activity against, Leishmania donovani promastigotes with IC50 of 30 mu g/mL and 51 mu g/mL, respectively.
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