Journal
BANGLADESH JOURNAL OF PHARMACOLOGY
Volume 4, Issue 1, Pages 65-68Publisher
BANGLADESH PHARMACOLOGICAL SOC
DOI: 10.3329/bjp.v4i1.1211
Keywords
Aegle marmelos; Antidiabetic activity; 6-methyl-4-chromanone; Skimmianine
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In vitro The methanol extract of the root of Aegle marmelos, a medicinal plant, was fractionated into eight fractions using column chromatography. The antidiabetic activity of all the fractions was studied using the glucose uptake by isolated rat hemi-diaphragm in vitro model. Using the bioassay-guided fractionation, two compounds 1 and 2 were isolated by column chromatography and identified as 6-methyl-4-chromanone and skimmianine respectively by NMR and mass spectral methods.
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