p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

(2014) Anne Simonsen et al.   Autophagy

Drosophila Atg7: Required for stress resistance, longevity and neuronal homeostasis, but not for metamorphosis

(2014) Gábor Juhász et al.   Autophagy

The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates

(2014) Karine Lindmo et al.   Autophagy

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

(2014) Wen-Xing Ding et al.   Autophagy

Eating on the fly: Function and regulation of autophagy during cell growth, survival and death in Drosophila

(2014) Thomas P. Neufeld et al.   Autophagy

The role of TOR in autophagy regulation from yeast to plants and mammals

(2014) Sandra Díaz-Troya et al.   Autophagy

ESCRT functions in autophagy and associated disease

(2011) Tor Erik Rusten et al.   CELL CYCLE

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

(2011) Trond Lamark et al.   CELL CYCLE

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection

(2010) Brigit E. Riley et al.   JOURNAL OF CELL BIOLOGY

The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy

(2010) Maria Filimonenko et al.   MOLECULAR CELL

The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer's Disease Hippocampus

(2009) Jeroen J.M. Hoozemans et al.   AMERICAN JOURNAL OF PATHOLOGY

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Shigella Phagocytic Vacuolar Membrane Remnants Participate in the Cellular Response to Pathogen Invasion and Are Regulated by Autophagy

(2009) Nicolas Dupont et al.   Cell Host & Microbe

Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes

(2009) Anne Simonsen et al.   JOURNAL OF CELL BIOLOGY

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Dimerisation of the UBA Domain of p62 Inhibits Ubiquitin Binding and Regulates NF-κB Signalling

(2009) Jed Long et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibition of Autophagy Induction Delays Neuronal Cell Loss Caused by Dysfunctional ESCRT-III in Frontotemporal Dementia

(2009) J.-A Lee et al.   JOURNAL OF NEUROSCIENCE

Listeria monocytogenes ActA-mediated escape from autophagic recognition

(2009) Yuko Yoshikawa et al.   NATURE CELL BIOLOGY

Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration

(2009) Sara Rollinson et al.   NEUROBIOLOGY OF AGING

Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: Their relation to AD common pathology

(2009) Ai Kadokura et al.   NEUROPATHOLOGY

Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila

(2009) Daijun Ling et al.   PLoS One

The cell biology of autophagy in metazoans: a developing story

(2008) A. Melendez et al.   DEVELOPMENT

Nutrient Deprivation Induces Neuronal Autophagy and Implicates Reduced Insulin Signaling in Neuroprotective Autophagy Activation

(2008) Jessica E. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ref(2)P, theDrosophila melanogasterhomologue of mammalian p62, is required for the formation of protein aggregates in adult brain

(2008) Ioannis P. Nezis et al.   JOURNAL OF CELL BIOLOGY

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

(2008) Malene Hansen et al.   PLoS Genetics