Phospholipase C-zeta deficiency as a cause for repetitive oocyte fertilization failure during ovarian stimulation for in vitro fertilization with ICSI: a case report

A plea for caution and more research in the ‘experimental’ use of ionophores in ICSI

(2015) Jonathan van Blerkom et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Live birth after artificial oocyte activation using a ready-to-use ionophore: a prospective multicentre study

(2015) Thomas Ebner et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Treatment with Ca2+ ionophore improves embryo development and outcome in cases with previous developmental problems: a prospective multicenter study

(2014) T. Ebner et al.   HUMAN REPRODUCTION

Protein phospholipase C Zeta1 expression in patients with failed ICSI but with normal sperm parameters

(2014) Hoi Chang Lee et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Ontogeny of the ovary in polycystic ovary syndrome

(2013) Daniel A. Dumesic et al.   FERTILITY AND STERILITY

Neonatal and neurodevelopmental outcome of children aged 3–10years born following assisted oocyte activation

(2013) Frauke Vanden Meerschaut et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Oocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology

(2012) Walaa M Ramadan et al.   Cell Communication and Signaling

Application of a ready-to-use calcium ionophore increases rates of fertilization and pregnancy in severe male factor infertility

(2012) Thomas Ebner et al.   FERTILITY AND STERILITY

Variance in total levels of phospholipase C zeta (PLC-ζ) in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability

(2012) Junaid Kashir et al.   FERTILITY AND STERILITY

Recombinant human phospholipase C zeta 1 induces intracellular calcium oscillations and oocyte activation in mouse and human oocytes

(2012) S.-Y. Yoon et al.   HUMAN REPRODUCTION

The benefit of artificial oocyte activation is dependent on the fertilization rate in a previous treatment cycle

(2012) Markus Montag et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Aberrant spindle structures responsible for recurrent human metaphase I oocyte arrest with attempts to induce meiosis artificially

(2011) B. Heindryckx et al.   HUMAN REPRODUCTION

Case report: live birth following ICSI with non-vital frozen-thawed testicular sperm and oocyte activation with calcium ionophore

(2011) Astrid Stecher et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Complete Fertilization Failure in ICSI

(2010) Kaoru YANAGIDA   Human Cell

Artificial oocyte activation using calcium ionophore in ICSI cycles with spermatozoa from different sources

(2010) Edson Borges et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Complete globozoospermia associated with PLCζ deficiency treated with calcium ionophore and ICSI results in pregnancy

(2009) S.L. Taylor et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Transitioning from egg to embryo: Triggers and mechanisms of egg activation

(2008) Vanessa L. Horner et al.   DEVELOPMENTAL DYNAMICS

The pattern of localization of the putative oocyte activation factor, phospholipase C , in uncapacitated, capacitated, and ionophore-treated human spermatozoa

(2008) P. Grasa et al.   HUMAN REPRODUCTION

Human sperm devoid of PLC, zeta 1 fail to induce Ca2+ release and are unable to initiate the first step of embryo development

(2008) Sook-Young Yoon et al.   JOURNAL OF CLINICAL INVESTIGATION