Association of signaling transducers and activators of transcription 1 and systemic lupus erythematosus

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

(2013) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Ubiquitin-Specific Protease 13 Regulates IFN Signaling by Stabilizing STAT1

(2013) H.-M. Yeh et al.   JOURNAL OF IMMUNOLOGY

The role of B lymphocyte stimulator in B cell biology: implications for the treatment of lupus

(2013) JL Scholz et al.   LUPUS

The interferon signature andSTAT1expression in rheumatoid arthritis synovial fluid macrophages are induced by tumor necrosis factor α and counter-regulated by the synovial fluid microenvironment

(2012) Rachael A. Gordon et al.   ARTHRITIS AND RHEUMATISM

Plasmacytoid dendritic cells control B cell-derived IL-10 production

(2012) Philipp Georg et al.   AUTOIMMUNITY

The role of activation-induced deaminase in Lupus Nephritis

(2012) Marilyn Diaz   AUTOIMMUNITY

Decreased microRNA(miR)-145 and increased miR-224 expression in T cells from patients with systemic lupus erythematosus involved in lupus immunopathogenesis

(2012) M-C. Lu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes

(2012) Stephanie Boisson-Dupuis et al.   CURRENT OPINION IN IMMUNOLOGY

Mice Deficient in STAT1 but Not STAT2 or IRF9 Develop a Lethal CD4+ T-Cell-Mediated Disease following Infection with Lymphocytic Choriomeningitis Virus

(2012) M. J. Hofer et al.   JOURNAL OF VIROLOGY

Activation of Oas1a gene expression by type I IFN requires both STAT1 and STAT2 while only STAT2 is required for Oas1b activation

(2012) Joanna A. Pulit-Penaloza et al.   VIROLOGY

Interferon signals and monocytic sensitization of the interferon-γ signaling pathway in the peripheral blood of patients with rheumatoid arthritis

(2011) Thomas Karonitsch et al.   ARTHRITIS AND RHEUMATISM

Regulatory and pathogenetic mechanisms of autoantibodies in SLE

(2011) Marko Radic et al.   AUTOIMMUNITY

Th Subset Balance in Lupus Nephritis

(2011) Katsuhisa Miyake et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Aim2 Deficiency in Mice Suppresses the Expression of the Inhibitory Fc  Receptor (Fc RIIB) through the Induction of the IFN-Inducible p202, a Lupus Susceptibility Protein

(2011) R. Panchanathan et al.   JOURNAL OF IMMUNOLOGY

Distinct Regulation of Murine Lupus Susceptibility Genes by the IRF5/Blimp-1 Axis

(2011) R. Panchanathan et al.   JOURNAL OF IMMUNOLOGY

Melatonin attenuates brain contusion-induced oxidative insult, inactivation of signal transducers and activators of transcription 1, and upregulation of suppressor of cytokine signaling-3 in rats

(2011) Ming Che Tsai et al.   JOURNAL OF PINEAL RESEARCH

Multidimensional Single Cell Based STAT Phosphorylation Profiling Identifies a Novel Biosignature for Evaluation of Systemic Lupus Erythematosus Activity

(2011) Xinfang Huang et al.   PLoS One

A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE

(2010) Johanna K Sandling et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Aim2 Deficiency Stimulates the Expression of IFN-Inducible Ifi202, a Lupus Susceptibility Murine Gene within the Nba2 Autoimmune Susceptibility Locus

(2010) R. Panchanathan et al.   JOURNAL OF IMMUNOLOGY

Identification of a Common Lupus Disease-Associated microRNA Expression Pattern in Three Different Murine Models of Lupus

(2010) Rujuan Dai et al.   PLoS One

Therapeutic Applications and Mechanisms Underlying the Activity of Immunosuppressive Oligonucleotides

(2009) Dennis M. Klinman et al.   Annals of the New York Academy of Sciences

Activation of the interferon-γ signaling pathway in systemic lupus erythematosus peripheral blood mononuclear cells

(2009) Thomas Karonitsch et al.   ARTHRITIS AND RHEUMATISM

High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups

(2009) Bahram Namjou et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

PDC expressing CD36, CD61 and IL-10 may contribute to propagation of immune tolerance

(2009) Marijo Parcina et al.   AUTOIMMUNITY

A tolerogenic peptide that induces suppressor of cytokine signaling (SOCS)-1 restores the aberrant control of IFN-γ signaling in lupus-affected (NZB×NZW)F1 mice

(2009) Amir Sharabi et al.   CLINICAL IMMUNOLOGY

Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

(2009) Xiaoyu Hu et al.   IMMUNOLOGICAL REVIEWS

Stage Dependent Aberrant Regulation of Cytokine-STAT Signaling in Murine Systemic Lupus Erythematosus

(2009) Matthew B. Hale et al.   PLoS One

STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk

(2008) A-K Abelson et al.   ANNALS OF THE RHEUMATIC DISEASES

Inteferons pen the JAK–STAT pathway

(2008) Christian Schindler et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY