Targeting lymphocyte co-stimulation: From bench to bedside

Regulatory T Cell Expression of Herpesvirus Entry Mediator Suppresses the Function of B and T Lymphocyte Attenuator-Positive Effector T Cells

(2014) R. Tao et al.   JOURNAL OF IMMUNOLOGY

IL-12-Impaired and IL-12-Secreting Dendritic Cells Produce IL-23 upon CD154 Restimulation

(2014) E. Jasny et al.   JOURNAL OF IMMUNOLOGY

Amphoteric liposomes enable systemic antigen-presenting cell-directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis

(2009) Evangelos Andreakos et al.   ARTHRITIS AND RHEUMATISM

Yin-Yang of costimulation: crucial controls of immune tolerance and function

(2009) Roza I. Nurieva et al.   IMMUNOLOGICAL REVIEWS

The significance of OX40 and OX40L to T-cell biology and immune disease

(2009) Michael Croft et al.   IMMUNOLOGICAL REVIEWS

The clinical utility of inhibiting CD28-mediated costimulation

(2009) Peter S. Linsley et al.   IMMUNOLOGICAL REVIEWS

Herpesvirus Entry Mediator-Ig Treatment during Immunization Aggravates Rheumatoid Arthritis in the Collagen-Induced Arthritis Model

(2009) M. Pierer et al.   JOURNAL OF IMMUNOLOGY

BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice

(2009) Wayne Truong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CD40–CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

(2009) Giandomenica Iezzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study

(2008) M H Buch et al.   ANNALS OF THE RHEUMATIC DISEASES

Development of autoimmune hepatitis-like disease and production of autoantibodies to nuclear antigens in mice lacking B and T lymphocyte attenuator

(2008) Yoshihiro Oya et al.   ARTHRITIS AND RHEUMATISM

The effect of anti-CD40 ligand in immune thrombocytopenic purpura

(2008) Vivek L. Patel et al.   BRITISH JOURNAL OF HAEMATOLOGY

A crucial role for HVEM and BTLA in preventing intestinal inflammation

(2008) Marcos W. Steinberg et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Association of the co-stimulator OX40L with systemic lupus erythematosus

(2008) Harinder Manku et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial

(2008) Nicolino Ruperto et al.   LANCET

Interaction of human PD-L1 and B7-1

(2008) Manish J. Butte et al.   MOLECULAR IMMUNOLOGY

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS

CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator

(2008) Guifang Cai et al.   NATURE IMMUNOLOGY

The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

(2008) Aurelie T Bauquet et al.   NATURE IMMUNOLOGY

CTLA4Ig treatment in patients with multiple sclerosis: An open-label, phase 1 clinical trial

(2008) V. Viglietta et al.   NEUROLOGY

A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis

(2008) Allison L Smitten et al.   ARTHRITIS RESEARCH & THERAPY

Abatacept inhibits progression of structural damage in rheumatoid arthritis: results from the long-term extension of the AIM trial

(2007) H K Genant et al.   ANNALS OF THE RHEUMATIC DISEASES

Platelet pro-aggregatory effects of CD40L monoclonal antibody

(2007) Maribel Mirabet et al.   MOLECULAR IMMUNOLOGY