Article
Orthopedics
C. M. Lawrie, R. L. Barrack, R. M. Nunley
Summary: The study showed that young, active patients undergoing modular DM total hip arthroplasty had favorable clinical outcomes and metal ion levels at mid-term follow-up, with excellent overall survivorship and minimal concerns regarding corrosion and metal ion release.
BONE & JOINT JOURNAL
(2021)
Article
Engineering, Biomedical
Therese Bormann, Laura Nebel, Ulrike Mueller, Phuong Thao Mai, Jens Gibmeier, Tobias Renkawitz, J. Philippe Kretzer
Summary: Corrosion at the modular taper junctions in total hip arthroplasty is clinically relevant. In vitro tribo-corrosion tests using FeCl3 and H2O2 can provide more severe and realistic testing conditions compared to pure saline or calf serum.
ACTA BIOMATERIALIA
(2022)
Article
Orthopedics
Giuseppe Solarino, Giovanni Vicenti, Massimiliano Carrozzo, Guglielmo Ottaviani, Biagio Moretti, Luigi Zagra
Summary: Modular neck implants can restore hip anatomy and are suitable for patients requiring complex reconstruction, but caution is needed for those with a high body mass index or requiring long-term use.
EFORT OPEN REVIEWS
(2021)
Article
Orthopedics
Annsley Mace, Charley M. Goodwin, Jeremy L. Gilbert
Summary: This study evaluated the assembly of two types of acetabular components with different geometries under a seating load. The results showed no significant difference in liner displacement between the two groups, and both designs exhibited minimal metal ion dissolution. This study provides important clinical insights into the impact of implant design on fretting corrosion.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Review
Orthopedics
Sravya P. Vajapey, Vivek M. Shah, Daniel M. Estok
Summary: Trunnion in total hip arthroplasty is the interface between the neck of a femoral stem and the femoral head. Complications arising from damage to this junction, known as MACC or trunnionosis, have increased with the use of modular hip prostheses. Factors such as taper design, implant metallurgical properties, and size mismatch of the bearing couple contribute to this condition.
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
(2023)
Article
Engineering, Biomedical
Eileen S. Cadel, L. D. Timmie Topoleski, Oleg Vesnovsky, Charles R. Anderson, Robert H. Hopper, Charles A. Engh, Matthew A. Di Prima
Summary: Corrosion and wear are commonly found at the taper-trunnion connection of modular total hip arthroplasty explanted devices. M/M modular connections exhibit more damage than C/M connections, but both are susceptible to damage. Analysis techniques show that stem trunnions have more damage than head tapers, and C/M connections have less corrosion and wear compared to M/M connections.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2022)
Article
Orthopedics
Matthew T. Houdek, Michael J. Taunton, Cody C. Wyles, Paul J. Jannetto, David G. Lewallen, Daniel J. Berry
Summary: This study showed that in patients with ALTR, the levels of Co and Cr in synovial fluid were significantly higher compared to whole blood. The synovial fluid Co ion concentration was the most accurate predictor of ALTR.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Orthopedics
Francesco Castagnini, Barbara Bordini, Monica Cosentino, Enrico Tassinari, Giulia Guizzardi, Francesco Traina
Summary: This study compared the outcomes of single taper (ST) and dual taper (DT) versions of the same stem design in total hip arthroplasty (THA). The results showed no significant differences in survival rates and hazard ratios for failures between the two versions. Similarly, there were no significant differences when stem-focused endpoints were considered. Therefore, the ST and DT versions of the same stem design have similar outcomes in terms of failure rates and survival rates at 5 years.
JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
(2023)
Review
Orthopedics
Theodore T. T. Manson, Murillo Adrados, Jeremy M. M. Gililland, Bilal M. M. Mahmood, Linsen T. T. Samuel, Joseph T. T. Moskal
Summary: Dual mobility (DM) is a widely used option for total hip replacement, which features a small inner head within a larger outer polyethylene head. It aims to increase stability and range of motion in the hip joint. However, long-term data, especially for modular DM implants, is lacking, and potential issues include accelerated polyethylene wear, intraprosthetic dislocation, and modular backside fretting corrosion.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2023)
Article
Orthopedics
Samo K. Fokter, Nenad Gubeljak, Jozef Predan, Jure Sevsek, Jan Zajc, Zmago Krajnc
Summary: This report discusses the case of bilateral modular neck fracture in a patient who underwent primary bi-modular total hip arthroplasty, occurring 3 years on one side and 20 years on the other side after implantation. Despite same surgeon and neck length used for both operations, fractures occurred with a 17-year time difference, highlighting the unpredictable nature of such complications. Orthopedic surgeons should exercise caution when using bi-modular stem designs for primary THA.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Engineering, Biomedical
Ulrike Mueller, Therese Bormann, Stefan Schroeder, Tobias Renkawitz, J. Philippe Kretzer
Summary: This study aims to evaluate different analytical approaches for assessing fretting corrosion behavior in modular taper connections in total hip replacement and determine the impact of four design variables. The findings suggest that taper engagement situation is the main factor predicting metal ion release, and the selection of appropriate analytical methods is crucial for evaluating corrosion behavior.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Medicine, General & Internal
Hiroki Wakabayashi, Masahiro Hasegawa, Yohei Naito, Shine Tone, Akihiro Sudo
Summary: This study assessed the long-term outcomes of total hip arthroplasty with a metal-on-metal acetabular prosthesis, revealing a 29.0% prevalence of pseudotumors and the importance of regular clinical surveillance for early detection of adverse reactions to metal debris.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Engineering, Biomedical
Eric S. Ouellette, Dongkai Zhu, Yangping Liu, Jeremy L. Gilbert
Summary: Soft gasket-like polymer films can inhibit fretting corrosion in total joint implants. Self-reinforced composites made from SRC-PEEK or SRC-PE show promise in limiting or preventing mechanically assisted corrosion. The use of SRC gaskets reduces fretting corrosion currents, with SRC-PEEK performing better than SRC-PE, and there is minimal wear damage.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2022)
Article
Orthopedics
John R. Steele, Aarti A. Shenoy, Ashley Pekmezian, Timothy Wright, Douglas E. Padgett
Summary: This study investigated shell-liner corrosion in modular dual mobility (MDM) acetabular components used in total hip arthroplasty. The results showed that liner corrosion was higher in MDM2 compared to MDM1, particularly outside the taper region. The findings suggest that factors related to design and surface finish play a significant role in the corrosion behavior of MDM components.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Medicine, General & Internal
Francesco Castagnini, Barbara Bordini, Monica Cosentino, Michele Di Liddo, Giuseppe Tella, Claudio Masetti, Francesco Traina
Summary: The study investigates the impact of age and sex on femoral component choices in modular total hip arthroplasty (THA). The results show that larger stem sizes are more common in males and elder patients. Standard necks are more commonly used in males aged 40-59 and less commonly used in males aged 70 or older. Different types of neck corrections are more prevalent in specific age and sex groups.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Michael-Alexander Malahias, Alex Gu, Shawn S. Richardson, Ivan De Martino, Peter K. Sculco, Alexander S. McLawhorn
Summary: The study found that the conversion rate from hip arthroscopy to total hip arthroplasty within two years is unacceptably high in Medicare osteoarthritis patients. Patients who underwent hip arthroscopy before total hip arthroplasty were at an increased risk of revision surgery, periprosthetic joint infection, and aseptic loosening within two years post arthroplasty.
Article
Orthopedics
Michael-Alexander Malahias, Alex Gu, Shawn S. Richardson, Ivan De Martino, David J. Mayman, Thomas P. Sculco, Peter K. Sculco
Summary: Recent studies have found that patients with preoperative lumbar degenerative disease (LDD) may have an increased risk of all-cause revision surgery within 2 years after total knee arthroplasty (TKA). Additionally, patients with LDD who have undergone lumbar fusion are also at a higher risk of TKA revision.
JOURNAL OF KNEE SURGERY
(2021)
Article
Orthopedics
Safa C. Fassihi, Michael-Alexander Malahias, Alex Gu, Shawn S. Richardson, Leonard T. Buller, Seth Stake, Ivan De Martino, Neil Pathak, Aaron Z. Chen, Michael P. Ast, Peter K. Sculco
Summary: This study found that same day or rapid discharge may be a feasible alternative to traditional inpatient treatment for patients undergoing total knee arthroplasty. There were no significant differences in complication and revision rates between the same day discharge group and either the rapid discharge or traditional discharge group, but patients in the rapid discharge group were less likely to require manipulation under anesthesia or develop periprosthetic joint infection at 1 year postoperatively when compared with the traditional discharge group.
JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
(2021)
Article
Orthopedics
Giorgio Perino, Ivan De Martino, Lingxin Zhang, Zhidao Xia, Jiri Gallo, Shonali Natu, David Langton, Monika Huber, Anastasia Rakow, Janosch Schoon, Enrique Gomez-Barrena, Veit Krenn
Summary: The histopathological examination of periprosthetic soft tissue and bone has helped identify and describe the morphological features of ALTR/ARMD. A uniform vocabulary and clarification of classification parameters are considered essential for meaningful interdisciplinary evaluation.
EFORT OPEN REVIEWS
(2021)
Review
Orthopedics
Fabio Mancino, Vincenzo Di Matteo, Fabrizio Mocini, Giorgio Cacciola, Giuseppe Malerba, Carlo Perisano, Ivan De Martino
Summary: A systematic review of 18 articles found that the all-cause reoperation-free survivorship of PFR implants was 76.6%. The overall complication rate was 27.2%, with dislocation being the most common complication. Patients showed improved postoperative hip scores.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Orthopedics
Raffaele Vitiello, Carlo Perisano, Tommaso Greco, Luigi Cianni, Chiara Polichetti, Rocco Maria Comodo, Ivan De Martino, Vincenzo La Vergata, Giulio Maccauro
Summary: This study analyzed the efficacy of a single type of intramedullary nailing or hip megaprosthesis in the treatment of metastases in the trochanteric region of the femur. The results showed that compared to the megaprostheses group, the intramedullary group had a shorter operative time and higher functional scores after surgery, but patients in this group may experience malnutrition and a pro-inflammatory state. The type of surgery, surgery duration, and the ratio of white blood cells to neutrophils were found to affect functional recovery. Overall, intramedullary nailing allows for rapid functional recovery, while hip megaprosthesis is more suitable for patients with a better prognosis.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Orthopedics
Ivan De Martino, Fabio Mancino, Vincenzo Di Matteo, Alessandro Singlitico, Giulio Maccauro, Giorgio Gasparini
Summary: The purpose of this study was to determine the minimum 10-year results of tantalum cones in revision total knee arthroplasty (TKA). The study found that metaphyseal fixation with tantalum cones demonstrated excellent survivorship and fixation at a minimum follow-up of 10 years, with no evidence of implant loosening or migration. This type of metaphyseal reconstruction can be a durable option for patients with massive bone defects.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Medicine, General & Internal
Giorgio Cacciola, Fabio Mancino, Lukas A. A. Holzer, Federico De Meo, Ivan De Martino, Antongiulio Bruschetta, Salvatore Risitano, Luigi Sabatini, Pietro Cavaliere
Summary: This study aimed to investigate the potential association between C-reactive protein (CRP) to Albumin ratio (CAR) and 30-day mortality after a hip fracture, and to evaluate the reliability of CAR Receiving Operating Characteristics curve (ROC) as a predictor of early mortality. The retrospective analysis included 676 patients (>65 years) treated for hip fracture between 2006 and 2018. Higher preoperative CAR levels were found to be associated with higher 30-day mortality. The area under the ROC curve for predicting 30-day mortality was reported as 0.816, with a cut-off value of 14.72 showing a specificity of 87% and a sensitivity of 40.8%. Patients older than 65 years with increased preoperative CAR levels were more likely to experience higher 30-day mortality. Despite moderate sensitivity, CAR should be considered a standard predictive marker due to its low cost and predictivity.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Fabio Mancino, Vincenzo Di Matteo, Fabrizio Mocini, Silvia Pietramala, Alessandro Singlitico, Andrea De Fazio, Vincenzo La Vergata, Giorgio Gasparini, Giulio Maccauro, Ivan De Martino
Summary: 3-D printed metal cones are a reliable option for the treatment of metaphyseal bone defects, with good short-term survivorship and low complication rates.
ORTHOPEDIC REVIEWS
(2022)
Review
Orthopedics
Fabio Mancino, Christopher W. Jones, Francesco Benazzo, Alessandro Singlitico, Alessandro Giuliani, Ivan De Martino
Summary: Robotic-assisted total knee arthroplasty has shown early advantages in improving knee kinematics and functional outcomes, but long-term results and cost reduction are still awaited.
ORTHOPEDIC RESEARCH AND REVIEWS
(2022)
Article
Engineering, Biomedical
Adriano Cannella, Tommaso Greco, Chiara Polichetti, Ivan De Martino, Antonio Mascio, Giulio Maccauro, Carlo Perisano
Summary: Adverse Reaction to Metal Debris (ARMD) is a common complication after Total Hip Replacement (THR), especially in implants with Metal-on-Metal (MoM) and Large Diameter Heads (LDHs). However, ARMD can also occur in other types of implants. This case report presents a severe case of ARMD in a non-MoM THR patient, which was initially misdiagnosed and resulted in the development of a massive pseudotumor. The patient achieved complete recovery after a two-stage revision treatment.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2022)
Review
Orthopedics
Michael-Alexander Malahias, Fabio Mancino, Alex Gu, Marco Adriani, Ivan De Martino, Friedrich Boettner, Peter K. Sculco
Summary: This study found that IBG with mesh is an effective method for patients with acetabular bone defects. Most patients with moderate bone loss as well as patients with large superolateral defects can be successfully treated with IBG combined with mesh. However, there is limited data to suggest that IBG with mesh may be associated with decreased survival rates in patients with severe lateral defects combined with ischial or medial wall osteolysis who require combined medial and lateral meshes. In addition, patients with severe superomedial migration of the cup should not be treated with IBG and mesh.
Review
Geriatrics & Gerontology
Giorgio Cacciola, Fabio Mancino, Federico De Meo, Antongiulio Bruschetta, Ivan De Martino, Pietro Cavaliere
Summary: The incidence of periprosthetic fractures after TKA is on the rise due to the increasing number of surgeries and aging population. Understanding the characteristics and classification of these fractures is crucial for selecting the most appropriate treatment.
GERIATRIC ORTHOPAEDIC SURGERY & REHABILITATION
(2021)
Review
Orthopedics
Giorgio Cacciola, Fabio Mancino, Federico De Meo, Vincenzo Di Matteo, Peter K. Sculco, Pietro Cavaliere, Giulio Maccauro, Ivan De Martino
Summary: The systematic review focused on mid-term studies of medial pivot total knee arthroplasty, revealing low overall reoperation rate, comparable survivorship to other standard implants, and better high-end function compared to standard implants.
JOURNAL OF ORTHOPAEDICS
(2021)
Review
Orthopedics
Fabio Mancino, Francesco Falez, Fabrizio Mocini, Peter K. Sculco, Giulio Maccauro, Ivan De Martino
Summary: The use of VVC implants in primary TKA seems to show improved functional outcomes and good mid-term survivorship. However, caution should be exercised due to the lack of long-term study data.
JOURNAL OF ORTHOPAEDICS
(2021)
