Article
Clinical Neurology
Jessica A. Katanga, Calum A. Hamilton, Lauren Walker, Johannes Attems, Alan J. Thomas
Summary: Age-related hearing loss often accompanies mild cognitive impairment and dementia, and it is unclear whether specific dementia-related neuropathologies are a cause or consequence of this association. This study found that neuritic plaques and Lewy body disease were associated with higher odds of hearing impairment, while nonspecific amyloid deposition, neurofibrillary tangle staging, overall AD neuropathology level, and cerebrovascular disease did not show clear associations. These results suggest that there may be a link between dementia-related neuropathology and hearing loss.
Article
Geriatrics & Gerontology
Katharine K. Brewster, Mei-Chen Hu, Sigal Zilcha-Mano, Alexandra Stein, Patrick J. Brown, Melanie M. Wall, Steven P. Roose, Justin S. Golub, Bret R. Rutherford
Summary: The study found that older adults with treated hearing loss are at increased risk for depression and conversion to dementia. Baseline depression is a strong independent predictor of dementia development. Although the development or persistence of depression is associated with dementia, the mediation effect of depression on the relationship between hearing loss and dementia is minimal.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Review
Geriatrics & Gerontology
Davide Brotto, Francesco Benvegnu, Anna Colombo, Cosimo de Filippis, Alessandro Martini, Niccolo Favaretto
Summary: Hearing loss in the elderly is a common condition that may be associated with cognitive decline. It is crucial to critically review the mechanisms behind this association and consider the impact of dementia on hearing tests and cognitive assessment. This article aims to analyze diagnostic tests, treatment options, auditory processing, and rehabilitation strategies for hearing loss in the elderly, in order to improve management of this disability in this vulnerable population.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Clinical Neurology
Pauline H. Croll, Elisabeth J. Vinke, Nicole M. Armstrong, Silvan Licher, Meike W. Vernooij, Robert J. Baatenburg de Jong, Andre Goedegebure, M. Arfan Ikram
Summary: The study found that hearing loss was associated with lower cognitive function at baseline and accelerated cognitive decline on a memory test. However, after additional adjustment for non-linear age effects, the association between hearing loss and accelerated cognitive decline was non-significant.
JOURNAL OF NEUROLOGY
(2021)
Article
Geriatrics & Gerontology
Shaoqing Ge, Eleanor S. McConnell, Bei Wu, Wei Pan, XinQi Dong, Brenda L. Plassman
Summary: This study found that older adults with hearing loss and dual sensory loss experience faster rates of cognitive decline compared to those with normal sensory function, while there was no significant association between vision loss and cognitive decline.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Article
Geriatrics & Gerontology
Ulrich Hoppe, Thomas Hocke, Heinrich Iro
Summary: Hearing loss is a common disorder, especially among elderly people. This study investigates the relationship between pure-tone hearing loss, age, and speech perception using two different model approaches. The results show that speech scores depend on the type of hearing loss and age. Across the lifespan, speech recognition can decline by up to 25 percentage points for constant pure-tone thresholds, with a maximum decrease of 10 percentage points per decade.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Neurosciences
Katharine K. Brewster, Mei-Chen Hu, Melanie M. Wall, Patrick J. Brown, Sigal Zilcha-Mano, Steven P. Roose, Alexandra Stein, Justin S. Golub, Bret R. Rutherford
Summary: This study found an association between untreated age-related hearing loss and lower cognitive abilities, which improved when hearing aids were worn. Future research needs to use cognitive assessments validated for hearing loss to evaluate the neuropsychological profile of individuals with age-related hearing loss and identify those at risk for dementia.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Review
Geriatrics & Gerontology
Tao Yue, Yu Chen, Qi Zheng, Zihao Xu, Wei Wang, Guangjian Ni
Summary: The close connection between hearing and cognitive function has been confirmed by various studies, with ARHL seniors showing higher cognitive impairment rates. The correlation mechanism between ARHL and cognitive decline requires more research. Intervention for ARHL patients may reduce cognitive decline risk, but current cognitive screening tools have limitations and potential for integration.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Review
Cell Biology
Josh Turknett, Thomas R. Wood
Summary: This article highlights the importance of lifestyle and environment in the development of Alzheimer's Disease. It suggests that previous approaches focusing solely on biological processes have been inadequate, and calls for a holistic approach that incorporates cognitive demand as a primary factor for intervention.
Article
Geriatrics & Gerontology
Anna McDonough, Joshi Dookhy, Cathy McHale, Jennifer Sharkey, Siobhan Fox, Sean P. Kennelly
Summary: The study found that a significant proportion of people with MCI showed evidence of hearing impairment upon assessment. Most patients felt that a hearing test was an important part of their memory assessment, although some did not recall having the purpose of the test explained to them clearly. Patients generally provided positive feedback on the service itself, but some felt they did not receive adequate information about the results.
Article
Clinical Neurology
Patricia A. Boyle, Tianhao Wang, Lei Yu, Robert S. Wilson, Robert Dawe, Konstantinos Arfanakis, Julie A. Schneider, David A. Bennett
Summary: The study found that cognitive decline in old age is driven by a wide array of neuropathologies, with Alzheimer's disease, infarcts, non-Alzheimer's disease neurodegenerative diseases, and cerebrovascular conditions playing significant roles. While most pathological indices were associated with faster decline, they only accounted for a portion of the variation in decline, highlighting the complexity of cognitive ageing.
Review
Geriatrics & Gerontology
Xinxing Fu, Robert H. Eikelboom, Rong Tian, Bo Liu, Shuo Wang, Dona M. P. Jayakody
Summary: This systematic review found a significant association between hearing loss and cognitive impairment and dementia in older adults who speak a Sinitic tonal language.
INNOVATION IN AGING
(2023)
Review
Geriatrics & Gerontology
Emma Hooper, Laura J. E. Brown, Hannah Cross, Piers Dawes, Iracema Leroi, Christopher J. Armitage
Summary: This study investigated factors influencing the use of hearing aids among community residents with dementia and age-related hearing loss, using the Theoretical Domains Framework. The findings suggest that hearing aid use is influenced by proficiency in handling the device, positive experiential consequences, comfort or fit of the aid, person-environment interactions, and social reinforcement. The study highlights the importance of adopting a multifaceted approach to hearing aid interventions and the need for further high-quality research in this area.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Neurosciences
Roaa Zayed Atef, Bernhard Michalowsky, Anika Raedke, Moritz Platen, Wiebke Mohr, Franka Muehlichen, Jochen Rene Thyrian, Wolfgang Hoffmann
Summary: Hearing loss is common in people with dementia and can lead to social isolation and depression. This study suggests that the use of hearing aids may be associated with improvements in cognitive function, depression, and health-related quality of life in dementia patients.
JOURNAL OF ALZHEIMERS DISEASE
(2023)
Review
Geriatrics & Gerontology
Guo Ying, Guangran Zhao, Xianpeng Xu, Su Su, Xin Xie
Summary: Based on the evidence collected in this umbrella review, age-related hearing loss is significantly associated with cognitive impairment and dementia. Hearing loss may represent a high risk factor for cognitive impairment and dementia in older adults.
FRONTIERS IN AGING NEUROSCIENCE
(2023)