Article
Engineering, Industrial
Salvatore Scrivano, Baris Tan, Tullio Tolio
Summary: The main contribution of this study is presenting a computationally efficient methodology to simulate single-part continuous-flow manufacturing systems with assembly/disassembly machines, multiple loops, general layout, and general inter-event time distributions. By using graph theory, a new method is presented to identify the machines causing slowdown, blocking, and starvation in a general layout and determine the time before the occurrence of a state transition for each machine and the time before the fulfillment or depletion of each buffer. The proposed method is significantly faster than traditional methods, making it suitable for analyzing both discrete-flow and continuous-flow systems.
JOURNAL OF MANUFACTURING SYSTEMS
(2023)
Article
Chemistry, Multidisciplinary
Laurence C. Magalhaes, Luciano C. Magalhaes, Jhonatan B. Ramos, Luciano R. Moura, Renato E. N. de Moraes, Joao B. Goncalves, Wilian H. Hisatugu, Marcelo T. Souza, Luis N. L. de Lacalle, Joao C. E. Ferreira
Summary: Digitization and virtualization are key factors in the era of Industry 4.0. Digital twins can increase the efficiency of various productive sectors, but there are challenges in using this technology in a Flexible Manufacturing System (FMS). Existing solutions are often expensive and complex to implement. This study presents a low-cost digital twin method for FMS, which uses an ERP system module to digitize the physical entity and sensors to provide real-time information, improving production efficiency and management.
APPLIED SCIENCES-BASEL
(2022)
Article
Engineering, Chemical
Adrian Miqueo, Jose A. Yague-Fabra, Marta Torralba, Maria-Jose Oliveros, Guido Tosello
Summary: The demand for mass customization drives the need for more productive and flexible assembly operations. Walking-worker assembly lines offer advantages over fixed-worker systems. This article presents a parallel walking-worker assembly line for multiple products and evaluates its performance compared to semiautomated and manual fixed-worker lines. Simulation models were used to create challenging scenarios based on a real industrial case study. The results reveal that semiautomated parallel walking-worker lines can achieve 30% higher productivity than fixed-worker lines under high-mix low-volume demand conditions.
Article
Robotics
Gal Gorjup, Geng Gao, Anany Dwivedi, Minas Liarokapis
Summary: In response to the increasing demand for customized production, a flexible robotic assembly system has been developed. This system combines CAD based component localization, compliance control, and a multi-modal gripper for efficient programming of complex tasks. With a dedicated Graphical User Interface, the system can be easily configured for novel assemblies, showing high efficiency and effectiveness.
IEEE ROBOTICS AND AUTOMATION LETTERS
(2021)
Article
Engineering, Industrial
Shiquan Ling, Daqiang Guo, Yiming Rong, George Q. Huang
Summary: This research proposes a real-time data-driven synchronous reconfiguration of smart ACL workshops (Sync-RAS) under the Graduation Intelligent Manufacturing System (GiMS) by leveraging Industry 4.0 (I4.0) enabling technologies. Computer vision (CV) is employed to monitor and analyze the real-time operation process within the human-centric AC. In addition, an appropriate information-sharing architecture with scalability and reconfigurability is developed to coordinate the smooth reconfiguration of the smart ACL workshop in rapid response to the changing demands.
JOURNAL OF MANUFACTURING SYSTEMS
(2022)
Article
Engineering, Electrical & Electronic
Adrian Miqueo, Marcos Gracia-Cadarso, Marta Torralba, Francisco Gil-Vilda, Jose Antonio Yaguee-Fabra
Summary: This article uses an industrial case study to examine the performance of multi-model assembly lines using a simulation model. The results show that milkruns can protect the assembly lines from upstream process disturbances.
Article
Automation & Control Systems
Ilker Erdem, Gauti Asbjornsson, Henrik Kihlman
Summary: This study finds that active and flexible fixtures are essential for improving the efficiency of manufacturing systems, but fixturing solutions need a more universal approach. The formulation of multiple workpieces interacting with each other is proposed, along with the development of force control strategies. Performance evaluation is conducted through a series of experiments.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2021)
Article
Environmental Sciences
Xuesong Zhang, Hao Zhou, Chenxi Fu, Menghan Mi, Changshu Zhan, Duc Truong Pham, Amir M. Fathollahi-Fard
Summary: End-of-life (EOL) products are receiving increasing attention due to the decline in environmental resources and population growth. Disassembly is a crucial step in the reuse of EOL products, but it is highly uncertain and may not produce expected outcomes. Uncertainty disassembly takes into account changes in parts caused by product use, and can better coordinate tasks and match the remanufacturing process.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Quantum Science & Technology
Stavros Efthymiou, Marco Lazzarin, Andrea Pasquale, Stefano Carrazza
Summary: This study presents the first attempt to perform circuit-based quantum simulation using JIT compilation technique. It demonstrates that the novel approach simplifies implementation complexity without degrading performance.
Article
Multidisciplinary Sciences
Akiko Hatakeyama, Yuliia Shymko, Brigitte Hartmann, Romain Retureau, Claude Nogues, Marco Pasi, Malcolm Buckle
Summary: This study uses PhAST technology to investigate the structural changes of nucleosomes, revealing similarities and differences between nucleosome assembly and disassembly processes. The results suggest that the efficiency of DNA-histone binding is influenced by the DNA sequence and the amplitude of PhAST signals changes differently during assembly and disassembly. These findings provide new insights into the role of DNA sequence in gene expression regulation and shed light on how the intrinsic properties of DNA are integrated into the control of chromatin structure.
Article
Multidisciplinary Sciences
Nachuan Song, Yiwen Chu, Shuai Li, Yuhang Dong, Xiaoting Fan, Jianpu Tang, Yanfei Guo, Guangshuai Teng, Chi Yao, Dayong Yang
Summary: In this study, a cascade dynamic assembly/disassembly of DNA nanoframework (NF) was developed for the controlled delivery of Cas9 ribonucleoprotein (RNP). The NF was prepared using acrylamide-modified DNA to initiate hybridization chain reaction (HCR), allowing the incorporation of single-guide RNA and loading of Cas9 protein. The responsive release of Cas9 RNP was achieved through the specific disassembly of NF triggered by glutathione in cancer cells. In vitro and in vivo experiments demonstrated high gene editing efficiency in cancer cells, low toxicity in normal cells, and significant antitumor efficacy in a breast cancer mouse model.
Article
Multidisciplinary Sciences
You-jin Jung, Hyoseok Kim, Hae-Kap Cheong, Yong-beom Lim
Summary: The authors demonstrate a strategy to enhance the magnetic responsiveness of self-assembled peptide nanostructures by combining the concepts of perfect alpha-helix and rod-coil supramolecular building blocks. They develop a monomeric, nonpolar, and perfect alpha-helix and use it as the rod block of rod-coil amphiphiles for fabricating responsive assemblies.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Industrial
Kuo-Ching Ying, Pourya Pourhejazy, Chen-Yang Cheng, Ren-Siou Syu
Summary: This research extends the distributed assembly permutation flowshop scheduling problem to account for flexible assembly and sequence-independent setup times in a supply chain-like setting. Constructive heuristic and customised metaheuristic algorithms are proposed to solve this emerging scheduling extension, demonstrating higher performance compared to existing algorithms.
INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH
(2023)
Article
Engineering, Industrial
Mingxing Li, George Q. Huang
Summary: The new flexible assembly line system (FAL) can avoid traditional assembly line balancing problems, but still faces mismatches between production and logistics. The complexity of production-intralogistics processes is higher than considering production or logistics optimization separately. The advent of Industry 4.0 technology presents great potential to revolutionize production management concepts, but there is a lack of research on how to utilize real-time data to support production decisions.
INTERNATIONAL JOURNAL OF PRODUCTION ECONOMICS
(2021)
Article
Biochemistry & Molecular Biology
Genpei Zhang, Kai Yue, Anqi Wang, Weishen Zhong, Peipei Yang, Lei Wang, Xinwei Ye, Xiaochen Sun
Summary: This study investigated the mechanisms of self-assembly and disassembly of biomimetic peptides with different components and sequences. The results show that hydrophobic and hydrophilic interactions play crucial roles in the self-assembly and disassembly processes, and polyethylene glycol chain modification is necessary for disassembly.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)