Development and Validation of Fluorescence-Based and Automated Patch Clamp–Based Functional Assays for the Inward Rectifier Potassium Channel Kir4.1

Ion Channel Pharmacology Under Flow: Automation Via Well-Plate Microfluidics

(2012) C. Ian Spencer et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Selective Inhibition of the Kir2 Family of Inward Rectifier Potassium Channels by a Small Molecule Probe: The Discovery, SAR, and Pharmacological Characterization of ML133

(2011) Hao-Ran Wang et al.   ACS Chemical Biology

The disruption of central CO2 chemosensitivity in a mouse model of Rett syndrome

(2011) Xiaoli Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay

(2011) Qunyi Li et al.   ANALYTICAL BIOCHEMISTRY

IonFlux: A Microfluidic Patch Clamp System Evaluated with Human Ether-à-go-go Related Gene Channel Physiology and Pharmacology

(2011) Andrew P. Golden et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome

(2011) M. Paulais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery, Characterization, and Structure?Activity Relationships of an Inhibitor of Inward Rectifier Potassium (Kir) Channels with Preference for Kir2.3, Kir3.X, and Kir7.1

(2011) Rene Raphemot et al.   Frontiers in Pharmacology

Comparison of Human Ether-à-go-go Related Gene Screening Assays Based on IonWorks Quattro and Thallium Flux

(2010) Terry R. Bridal et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Profiling Diverse Compounds by Flux- and Electrophysiology-Based Primary Screens for Inhibition of Human Ether-à-go-go Related Gene Potassium Channels

(2010) Beiyan Zou et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating

(2010) Katherine Fallen et al.   Channels

Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel

(2010) G. Bhave et al.   MOLECULAR PHARMACOLOGY

Inwardly Rectifying Potassium Channels: Their Structure, Function, and Physiological Roles

(2010) Hiroshi Hibino et al.   PHYSIOLOGICAL REVIEWS

A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

(2009) Steven A. Titus et al.   ANALYTICAL BIOCHEMISTRY

High-Throughput Screening Reveals a Small-Molecule Inhibitor of the Renal Outer Medullary Potassium Channel and Kir7.1

(2009) L. M. Lewis et al.   MOLECULAR PHARMACOLOGY

Mutational and In Silico Analyses for Antidepressant Block of Astroglial Inward-Rectifier Kir4.1 Channel

(2009) K. Furutani et al.   MOLECULAR PHARMACOLOGY

Epilepsy, Ataxia, Sensorineural Deafness, Tubulopathy, andKCNJ10Mutations

(2009) Detlef Bockenhauer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2

(2009) E. Delpire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10

(2009) U. I. Scholl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breathing disorders in Rett syndrome: Progressive neurochemical dysfunction in the respiratory network after birth

(2009) David M. Katz et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

A Novel Assay of Gi/o-Linked G Protein-Coupled Receptor Coupling to Potassium Channels Provides New Insights into the Pharmacology of the Group III Metabotropic Glutamate Receptors

(2008) C. M. Niswender et al.   MOLECULAR PHARMACOLOGY