Evaluation of Cellular Impedance Measures of Cardiomyocyte Cultures for Drug Screening Applications

Impedance-Based Detection of Beating Rhythm and Proarrhythmic Effects of Compounds on Stem Cell-Derived Cardiomyocytes

(2011) Malin K.B. Jonsson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

(2011) HG Laverty et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dynamic monitoring of beating periodicity of stem cell-derived cardiomyocytes as a predictive tool for preclinical safety assessment

(2011) Yama A Abassi et al.   BRITISH JOURNAL OF PHARMACOLOGY

Distinguishing drug-induced minor morphological changes from major cellular damage via label-free impedimetric toxicity screening

(2011) Robert Meissner et al.   LAB ON A CHIP

Estimating the Risk of Drug-Induced Proarrhythmia Using Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes

(2011) Liang Guo et al.   TOXICOLOGICAL SCIENCES

Electrical cell-substrate impedance sensing as a non-invasive tool for cancer cell study

(2010) Jongin Hong et al.   ANALYST

Label-free whole-cell assays: expanding the scope of GPCR screening

(2010) Clay W Scott et al.   DRUG DISCOVERY TODAY

Label-free screening assays: a strategy for finding better drug candidates

(2010) Charles A Lunn   Future Medicinal Chemistry

Real-time monitoring of relaxation and contractility of smooth muscle cells on a novel biohybrid chip

(2010) Sina Haas et al.   LAB ON A CHIP

An evaluation of hERG current assay performance: Translating preclinical safety studies to clinical QT prolongation

(2010) Gary Gintant   PHARMACOLOGY & THERAPEUTICS

Integrated risk assessment and predictive value to humans of non-clinical repolarization assays

(2009) Robert M Wallis   BRITISH JOURNAL OF PHARMACOLOGY

Kinetic Cell-Based Morphological Screening: Prediction of Mechanism of Compound Action and Off-Target Effects

(2009) Yama A. Abassi et al.   CHEMISTRY & BIOLOGY

Gq-initiated cardiomyocyte hypertrophy is mediated by phospholipase Cβ1b

(2009) Theresa M. Filtz et al.   FASEB JOURNAL