Pre- and Posttreatment With Edaravone Protects CA1 Hippocampus and Enhances Neurogenesis in the Subgranular Zone of Dentate Gyrus After Transient Global Cerebral Ischemia in Rats

In Vivo and In Vitro Treatment With Edaravone Promotes Proliferation of Neural Progenitor Cells Generated Following Neuronal Loss in the Mouse Dentate Gyrus

(2012) Maho Kikuta et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia

(2012) Yanyan Sun et al.   Molecular Neurodegeneration

Loss of survivin in neural precursor cells results in impaired long-term potentiation in the dentate gyrus and CA1-region

(2012) E. Iscru et al.   NEUROSCIENCE

Post-stroke estradiol treatment enhances neurogenesis in the subventricular zone of rats after permanent focal cerebral ischemia

(2012) J. Zheng et al.   NEUROSCIENCE

Potentials of endogenous neural stem cells in cortical repair

(2012) Bhaskar Saha et al.   Frontiers in Cellular Neuroscience

mGluR5 is involved in proliferation of rat neural progenitor cells exposed to hypoxia with activation of mitogen-activated protein kinase signaling pathway

(2011) Lingyu Zhao et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injury

(2011) P. Zhang et al.   NEUROSCIENCE

Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils

(2011) Feng Lu et al.   NEUROSCIENCE LETTERS

AMN082 promotes the proliferation and differentiation of neural progenitor cells with influence on phosphorylation of MAPK signaling pathways

(2010) Yumei Tian et al.   NEUROCHEMISTRY INTERNATIONAL

A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation

(2010) Kazuya Motomura et al.   NEUROSCIENCE LETTERS

Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4

(2009) Kiyoshi Kikuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Edaravone, a free radical scavenger, mitigates both gray and white matter damages after global cerebral ischemia in rats

(2009) Kozue Kubo et al.   BRAIN RESEARCH

Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway

(2009) Nobuko Koshikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Edaravone Protects Against Apoptotic Neuronal Cell Death and Improves Cerebral Function After Traumatic Brain Injury in Rats

(2009) Tatsuki Itoh et al.   NEUROCHEMICAL RESEARCH

Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells

(2009) Masanori Yoneyama et al.   NEUROCHEMISTRY INTERNATIONAL

Hypoxia stimulates proliferation of rat neural stem cells with influence on the expression of cyclin D1 and c-Jun N-terminal protein kinase signaling pathway in vitro

(2009) X. Chen et al.   NEUROSCIENCE

Caspase-2 activation in neural stem cells undergoing oxidative stress-induced apoptosis

(2008) Christoffer Tamm et al.   APOPTOSIS

The Novel Antioxidant Edaravone: From Bench to Bedside

(2008) Toshiaki Watanabe et al.   Cardiovascular Therapeutics

Cilostazol preserves CA1 hippocampus and enhances generation of immature neuroblasts in dentate gyrus after transient forebrain ischemia in rats

(2008) Jeong Hyun Lee et al.   EXPERIMENTAL NEUROLOGY

Edaravone (MCI-186) Scavenges Reactive Oxygen Species and Ameliorates Tissue Damage in the Murine Spinal Cord Injury Model

(2008) Takeshi AOYAMA et al.   NEUROLOGIA MEDICO-CHIRURGICA

Ischemic stroke and neurogenesis in the subventricular zone

(2008) Rui Lan Zhang et al.   NEUROPHARMACOLOGY

Plasticity and repair in the post-ischemic brain

(2008) Massimiliano Di Filippo et al.   NEUROPHARMACOLOGY

Baicalein suppresses hypoxia-induced HIF-1α protein accumulation and activation through inhibition of reactive oxygen species and PI 3-kinase/Akt pathway in BV2 murine microglial cells

(2008) Keun Young Hwang et al.   NEUROSCIENCE LETTERS

Protocatechuic acid promotes cell proliferation and reduces basal apoptosis in cultured neural stem cells

(2008) Shui Guan et al.   TOXICOLOGY IN VITRO