MACC1 Expression Correlates with PFKFB2 and Survival in Hepatocellular Carcinoma

Akt phosphorylates HK-II at Thr-473 and increases mitochondrial HK-II association to protect cardiomyocytes.

(2013) David J. Roberts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt-dependent Activation of the Heart 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB2) Isoenzyme by Amino Acids

(2013) Laura Novellasdemunt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt inhibition promotes hexokinase 2 redistribution and glucose uptake in cancer cells

(2013) Catherine L. Neary et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Knockdown of MACC1 expression suppressed hepatocellular carcinoma cell migration and invasion and inhibited expression of MMP2 and MMP9

(2012) Jie Gao et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

MACC1 controls Met: What a difference an Sp1 site makes

(2011) Ulrike Stein et al.   CELL CYCLE

Androgen stimulates glycolysis forde novolipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells

(2010) Jong-Seok Moon et al.   BIOCHEMICAL JOURNAL

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Nuclear Targeting of 6-Phosphofructo-2-kinase (PFKFB3) Increases Proliferation via Cyclin-dependent Kinases

(2009) Abdullah Yalcin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer

(2009) Lisa A Boardman   Genome Medicine

Glycolytic enzyme inhibitors in cancer treatment

(2008) Roberto Scatena et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

p53 regulates glucose metabolism through an IKK-NF-κB pathway and inhibits cell transformation

(2008) Keiko Kawauchi et al.   NATURE CELL BIOLOGY

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis

(2008) Ulrike Stein et al.   NATURE MEDICINE