4.1 Review

Are Beta Blockers New Potential Anticancer Agents?

Journal

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
Volume 15, Issue 22, Pages 9567-9574

Publisher

ASIAN PACIFIC ORGANIZATION CANCER PREVENTION
DOI: 10.7314/APJCP.2014.15.22.9567

Keywords

Beta; blockers; adrenoceptors; anticancer; breast; ovarian; pancreatic; prostate

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beta-Blockers have been one of the most widely used and versatile drugs for the past half a century. A new potential for their use as anti-cancer drugs has emerged in the past few years. Various retrospective case control studies have been suggestive that use of beta-blockers before the diagnosis of cancer could have preventive and protective effects against non-small cell lung carcinoma, melanoma, and breast, pancreatic and prostate cancers. Experimental and clinical observations are still inconclusive with some inconsistent findings. However, indications are pointing toward a positive role of some beta-blockers against certain forms of cancers. This mini review is an effort to present the up to date published results of case-control studies and experimental findings.

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