Article
Anesthesiology
Yousof Fawzy, Zia Siddiqui, Samer Narouze, Sudheer Potru, Alyssa M. Burgart, Mercy A. Udoji
Summary: Workplace violence includes physical assault, threatening behavior, and verbal abuse targeting individuals in the workplace. Violence in healthcare settings, particularly pain clinics, is believed to be underreported due to hesitancy to report, lack of support from management and healthcare systems, and absence of institutional policies regarding patient violence against healthcare workers. This article explores the risk factors, costs, and impacts of workplace violence, provides guidance on establishing prevention programs, and addresses recovering from violence in the practice setting.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Anesthesiology
Gina Votta-Velis, Martha L. Daviglus, Alain Borgeat, Katharina Beckmann, Andrew Q. Ta, John L. Parker, Sasha Kravets, Olga L. Garcia, Amber Pirzada, Nicole Gastala, Valentina Valle, Jamie J. Benken, Maya Campara, Gabriela Aguiluz, Stavros G. Memtsoudis, Pier C. Giulianotti, Enrico Benedetti
Summary: This study evaluated the effectiveness of a surgical opioid-avoidance protocol (SOAP) on postoperative pain scores in a diverse patient population. The SOAP group, which followed a strict opioid-avoidance order set and received patient and staff education, showed non-inferior postoperative pain scores compared to the non-SOAP group. Additionally, the SOAP group had lower opioid consumption and fewer prescription opioids upon discharge.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Surgery
Eleah D. Porter, Sarah Y. Bessen, Ilda B. Molloy, Julia L. Kelly, Niveditta Ramkumar, Joseph D. Phillips, Andrew P. Loehrer, Matthew Z. Wilson, Rian M. Hasson, Srinivas J. Ivatury, Jessica R. Henkin, Richard J. Barth
Summary: This clinical trial validated a patient-centered opioid discharge prescription guideline that satisfied 93% of patients. FDA-compliant disposal of excess pills was achieved in 83% of patients with easily actionable interventions.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2021)
Article
Pediatrics
Asmamaw Emagn Kasahun, Ashenafi Kibret Sendekie, Rahel Belete Abebe
Summary: This study assessed the adequacy of pain management among pediatric patients at a hospital in Ethiopia. The results showed that more than half of the patients received inadequate pain medication, and the type of medication administered did not match the severity of the pain.
FRONTIERS IN PEDIATRICS
(2023)
Article
Oncology
Soraira Pacheco, Linh M. T. Nguyen, John M. Halphen, Nikitha N. Samy, Nathaniel R. Wilson, Gregory Sattler, Shane E. Wing, Christine Feng, Rex A. D. Paulino, Pulin Shah, Supriyanka Addimulam, Riddhi Patel, Curtis J. Wray, Joseph A. Arthur, David Hui
Summary: Patient prescriber agreements (PPAs) are recommended as a strategy for mitigating non-medical opioid use (NMOU) in cancer patients. Our study found that 54% of patients had a PPA, and 10% were not adherent. PPAs were associated with younger age and alcohol use, while non-adherence was associated with males, being single, tobacco and alcohol use, contact with persons involved in criminal activity, opioid use for non-cancer pain, and higher pain score.
Review
Geriatrics & Gerontology
Laura A. Dowd, Amanda J. Cross, Felicity Veal, Choon Ean Ooi, J. Simon Bell
Summary: Effective interventions can improve analgesic use and appropriateness in long-term care facilities. Interventions involving prescribers, pharmacists, and nurses, with an educational component, are most effective. Combining education and decision support also shows promise. Medication review interventions can lead to changes in medication prescription.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Anesthesiology
Karim S. Ladha, Kathak Vachhani, Gretchen Gabriel, Rasheeda Darville, Karl Everett, Jodi M. Gatley, Refik Saskin, Dorothy Wong, Praveen Ganty, Rita Katznelson, Alexander Huang, Joseph Fiorellino, Diana Tamir, Maxwell Slepian, Joel Katz, Hance Clarke
Summary: Patients who received Transitional Pain Service showed a faster reduction in opioid use compared to the control group. The difficulty in finding an appropriate control group highlights the need for future randomized controlled trials to determine efficacy.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Anesthesiology
Mingyang Sun, Wan-Ming Chen, Szu-Yuan Wu, Jiaqiang Zhang
Summary: This study aimed to investigate the association between presurgical sarcopenia and long-term non-opioid analgesic and opioid use after elective surgery under general anesthesia. The results showed that sarcopenia was associated with higher rates of long-term non-opioid analgesic and opioid use after surgery.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Anesthesiology
Eri C. Seng, Soraya Mehdipour, Sierra Simpson, Rodney A. Gabriel
Summary: Large language models like ChatGPT have become increasingly popular. Perioperative pain providers can utilize natural language processing (NLP) technology to improve patient care, such as tracking persistent postoperative opioid use. This proof-of-concept study demonstrated the ability of an NLP engine to accurately identify patients who had persistent opioid use after major spine surgery.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Anesthesiology
Tomoya Kuramochi, Makoto Sano, Ichie Kajiwara, Yukino Oshima, Tomoaki Itaya, Jinsuk Kim, Yoshimi Ichimaru, Osamu Kitajima, Atsushi Masamune, Hideaki Ijichi, Takahiro Suzuki
Summary: This study investigates the effects of tramadol on pancreatic ductal adenocarcinoma and finds that tramadol inhibits proliferation and invasion, increases anti-tumor macrophages, and decreases inflammatory cytokines, suggesting its potential use for pain management in cancer patients.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Multidisciplinary Sciences
Shoham Choshen-Hillel, Ido Sadras, Tom Gordon-Hecker, Shir Genzer, David Rekhtman, Eugene M. Caruso, Koby L. Clements, Adrienne Ohler, David Gozal, Salomon Israel, Anat Perry, Alex Gileles-Hillel
Summary: Adequate pain management is a challenge in healthcare, and this study finds that physicians working night shifts may have reduced empathy for patients' pain and prescribe fewer analgesics, especially opioids, likely due to sleep deprivation, fatigue, and stress.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Health Care Sciences & Services
Sarah Kosakowski, Allyn Benintendi, Pooja Lagisetty, Marc R. Larochelle, Amy S. B. Bohnert, Angela R. Bazzi
Summary: Patients on long-term opioid therapy for chronic pain described generally adverse experiences with opioid tapers. These tapers can lead to significant physical, emotional, and social consequences, often reducing trust and engagement in healthcare. Patient-provider relationships and communication play a crucial role in patients' perceptions of the quality and outcomes of opioid tapers.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Nursing
Laura Lorenzo Allegue, Leonor Laredo Velasco, Ana Maria Recio Vivas, Jose Miguel Mansilla Dominguez, Pedro Monino Ruiz, Luz Bueno Rey, Isabel Font-Jimenez, Emilio Vargas Castrillon
Summary: This study aims to describe the prevalence and characteristics of pain in adult hospitalized patients and analyze the concordance between patient-reported and recorded pain and its impact on analgesic management. The findings indicate that pain is often inadequately documented and half of patients with moderate to severe pain do not receive adequate pain management.
Article
Anesthesiology
Nanqi Li, Bing Chen, Gaogan Jia, Rui Xu, Ying Xia, Chuijin Lai, Gang Li, Wenxian Li, Yuan Han
Summary: This study found that neonatal pain can result in impaired hearing in adulthood, possibly due to increased dendritic spine density and reduced brain-derived neurotrophic factor levels in the auditory cortex.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Obstetrics & Gynecology
Ohad Gluck, Stav Amram, Ohad Feldstein, Elad Barber, Liliya Tamayev, Eran Weiner, Ben Oren, Shimon Ginath
Summary: The study aimed to investigate the effect of preemptive infiltration on postoperative pain and the use of analgesics after vaginal hysterectomy. A total of 120 patients who had undergone VH were included in the retrospective study. The results showed that preemptive infiltration group required a lower morphine dose in the recovery unit and less use of analgesia 24 hours after surgery. Evaluation: 7 points.
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
(2023)
Article
Nutrition & Dietetics
Hyunseong Kim, Jinyoung Hong, Junseon Lee, Wanjin Jeon, Changhwan Yeo, Yoonjae Lee, Seungho Baek, Inhyuk Ha
Summary: CAS pretreatment can protect hepatocytes from APAP-induced injury by inhibiting inflammation and oxidative stress through Sirt1/HO-1 signaling, suggesting its potential as a natural hepatoprotective drug.
Review
Integrative & Complementary Medicine
Seungwon Shin, Wonkyung Moon, Suran Kim, Seok Hee Chung, Jongwoo Kim, Namkwen Kim, Yoon Jae Lee, Minjung Park
Summary: This study reviewed the development, dissemination, and implementation of clinical practice guidelines (CPGs) in Korean Medicine (KM). KM-CPGs are developed and evaluated using standardized methods, with quality controlled through a tri-step appraisal process. The Steering Committee of the KoMIT project reviews and confirms the CPGs for public disclosure and dissemination.
INTEGRATIVE MEDICINE RESEARCH
(2023)
Article
Nutrition & Dietetics
Doori Park, Jee-Eun Yoon, Boram Choi, Yoon-Jae Lee, In-Hyuk Ha
Summary: Menopause is a hormone-deficiency state that causes various symptoms such as facial flushing, vaginal dryness, and depression. Hormone-replacement therapy is commonly used, but it has side effects. In this study, a complex extract of Polygonatum sibiricum and Nelumbinis semen was found to improve menopause symptoms without side effects by increasing the expression of ER beta and restoring vaginal epithelial cell thickness. It also improved blood-lipid metabolism and alleviated osteoporosis. Therefore, it could be a natural treatment option for menopause.
Review
Medicine, General & Internal
Sookyung Lee, Jiyoon Yeo, Sook-Hyun Lee, Yoon Jae Lee, Sangkwan Lee, In-Hyuk Ha
Summary: This study analyzed the distribution and healthcare utilization of patients with migraine in South Korea using data from 2010-2018. The study identified the treatments frequently used in Western and Korean medicine hospitals, as well as their frequency of use and costs. The findings can be used as a basis for relevant health policy decisions.
Article
Clinical Neurology
Hyo-Rim Jo, Yong-Gyun Kim, Won-Suk Sung, Kyoung Sun Park, Yoon Jae Lee, Sun Young Cho, Byung-Kwan Seo, Young-Ee Kwon, Eun-Jung Kim
Summary: This study aims to evaluate the efficacy and safety of SIKD1977 in treating postherpetic neuralgia (PHN) and determine an effective dose. It is a randomized, placebo-controlled, double-blind trial with 90 eligible participants. The study will provide evidence for the use of SIKD1977 in PHN treatment.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Health Care Sciences & Services
Bo-Kyung Hwang, Kyoung Sun Park, Seung-Hyeok Ku, Sung-Hyun Kim, Hyun-Woo Moon, Mi-So Park, Hye-Kyung Baek, Jin Namgoong, Seung-Yoon Hwangbo, Ji-Yeon Seo, Yoon Jae Lee, Jinho Lee, In-Hyuk Ha
Summary: This study conducted a randomized controlled clinical trial to compare the effectiveness of integrated Korean medicine (IKM) with herbal medicine treatment to IKM monotherapy for post-accident syndrome persistent after the acute phase. The results showed that the combination of IKM and herbal medicine significantly improved the overall post-accident syndrome persistent after the acute phase and relieved somatic pain, maintaining this effect for at least 17 weeks.
Review
Medicine, General & Internal
Eun Young Park, Jae-Heung Cho, Sook-Hyun Lee, Koh-Woon Kim, In-Hyuk Ha, Yoon Jae Lee
Summary: Acupuncture has been found to be effective in treating temporomandibular disorder (TMD), improving outcomes and reducing pain intensity. However, more well-designed clinical trials are needed to provide stronger evidence for its effectiveness.
Article
Clinical Neurology
Kyoung Sun Park, Changnyun Kim, Joo Won Kim, Sang-Don Kim, Jee Young Lee, Yoon Jae Lee, Jinho Lee, Min Ji Kim, Young Eun Choi, Changsop Yang, Chang-Hyun Han, In-Hyuk Ha
Summary: This study aimed to compare the effectiveness of pharmacopuncture and physical therapy in treating chronic lower back pain. The results showed that pharmacopuncture significantly reduced pain and improved functional outcomes and quality of life, compared to physical therapy. Therefore, pharmacopuncture could be recommended as a treatment option for patients with chronic lower back pain.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Clinical Neurology
Doori Kim, Eun-San Kim, Yoon Jae Lee, Jee Young Lee, Kyong Sun Park, So Young Jung, Changsop Yang, Chang-Hyun Han, In-Hyuk Ha
Summary: This study compared the efficacy, safety, and cost-effectiveness of non-pharmacological and pharmacological treatments for Lumbar disc herniation (LDH). The results showed that the non-pharmacological treatment group had significantly greater improvement and higher QALY value, with lower cost. This suggests that non-pharmacological treatment may be a more cost-effective approach.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Health Care Sciences & Services
Hyungsuk Kim, Jae Woo Shim, Woo-Chul Shin, Yoon Jae Lee, In-Hyuk Ha, Koh-Woon Kim, Jae-Heung Cho
Summary: Since the publication of the Korean Medicine Clinical Practice Guidelines (KMCPGs) for temporomandibular disorders (TMDs) in 2018, many new clinical research results have been published. Therefore, this study presents updated recommendations for TMD treatment based on current research data. Through a risk of bias assessment and meta-analysis, the draft version of the guidelines was determined and the final guidelines were derived using the Delphi method. Acupuncture, pharmacopuncture, and Chuna manual therapy are recommended for TMD patients, and a combination of Korean medicines with conventional therapy should be considered.
Article
Health Care Sciences & Services
Doori Kim, Soo-Jin Kim, Yoon Jae Lee, Chang Sop Yang, Chang-Hyun Han, In-Hyuk Ha
Summary: This study explored real-world patient experiences in clinical lumbar disc herniation (LDH) through a questionnaire survey. The most common symptoms were numbness in the leg and back pain, while the most common disabilities were discomfort in sitting and lifting. Back pain was identified as the highest priority symptom, and most respondents prioritized improvement in disability over pain, stable effect over rapid effect, and safety over treatment efficacy.
Article
Health Care Sciences & Services
Ye-Seul Lee, Yu-Cheol Lim, Jiyoon Yeo, Song-Yi Kim, Yoon Jae Lee, In-Hyuk Ha
Summary: Limited knowledge exists on the impact of neoadjuvant and adjuvant treatments on post-surgery lymphedema (LE) in breast cancer patients. A study using a national cohort from the Korean National Health Insurance Service database found that while minimal lymph node dissection reduced LE risk, neoadjuvant chemotherapy followed by lymph node dissection did not. Adjusting for adjuvant chemotherapy decreased LE risk in the lymph node dissection group, but not mortality risk. Longer duration of neoadjuvant chemotherapy, especially taxane-based, combined with lymph node dissection increased LE risk. This highlights the importance of early and long-term surveillance to reduce LE risk.
Review
Primary Health Care
Hyun-Ju Seo, Soo Young Kim, Yoon Jae Lee, Ji-Eun Park
Summary: Assessment of the risk of bias is essential for systematic reviews. The Risk of Bias Assessment Tool for Nonrandomized Studies (RoBANS) is a widely used tool for assessing bias in nonrandomized studies. The revised version, RoBANS 2, has shown acceptable reliability and validity, providing a comprehensive framework for evaluating bias in nonrandomized studies of interventions.
KOREAN JOURNAL OF FAMILY MEDICINE
(2023)
Review
Medicine, General & Internal
Hyungwook Ji, Seungwon Shin, Yongjoo Kim, In-Hyuk Ha, Doori Kim, Yoon Jae Lee
Summary: This study analyzed the trend of surgical service utilization in patients with lumbar spinal stenosis (LSS) in Korea from 2010 to 2019. The findings showed an increase in the number of claims and medical expenses for surgeries, with decompression accounting for a higher proportion of first surgeries and fusion being more common in second surgeries. Patients who underwent fusion procedures had longer hospital stays and higher medical expenses across all sex and age groups.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Yen Min Wang, Yu-Cheol Lim, Deok-Sang Hwang, Yoon Jae Lee, In-Hyuk Ha, Ye-Seul Lee
Summary: This study investigated the trends in osteoporosis-related treatments and overall anticancer drug treatments in Korean patients with breast cancer from 2010 to 2019. The results showed that osteoporosis-related treatment and patient age were associated with the prescriptions of anticancer drugs.
MEDICINA-LITHUANIA
(2023)