Article
Cardiac & Cardiovascular Systems
Markus S. Anker, Sophia K. Potthoff, Alessia Lena, Jan Porthun, Sara Hadzibegovic, Ruben Evertz, Corinna Denecke, Ann-Kathrin Froehlich, Frederike Sonntag, Vera Regitz-Zagrosek, Stuart D. Rosen, Alexander R. Lyon, Thomas F. Luescher, John A. Spertus, Stefan D. Anker, Mahir Karakas, Lars Bullinger, Ulrich Keller, Ulf Landmesser, Javed Butler, Stephan von Haehling
Summary: This study compared the EORTC QLQ-C30 and ESC HeartQoL questionnaires for assessing health-related quality of life in cancer patients, and found that both instruments were associated with increased mortality in cancer patients. Combining both questionnaires provided even greater stratification of patient risk.
EUROPEAN JOURNAL OF HEART FAILURE
(2023)
Article
Multidisciplinary Sciences
Mikiyas Amare Getu, Panpan Wang, Eva Johanna Kantelhardt, Edom Seife, Changying Chen, Adamu Addissie
Summary: This study aimed to examine the validity and reliability of the EORTC QLQ-BR45 questionnaire among breast cancer patients in Ethiopia. The results showed that the questionnaire has good reliability and validity, and can be used to assess the quality of life of breast cancer patients.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Rachel S. van Leeuwaarde, Angelica M. Gonzalez-Clavijo, Marc Pracht, Galina Emelianova, Winson Y. Cheung, Christina Thirlwell, Kjell Oberg, Francesca Spada
Summary: This study aims to assess patients' perceptions of the EORTC QLQ-C30 and EORTC QLQ-G.I.NET21 questionnaires in neuroendocrine neoplasms (NENs). The study found that there are limitations in the design of the questions and the patients' satisfaction reporting of the questionnaire.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Nern Hoong Kao, N. Gopalakrishna Iyer, Alice Chua, Rahul Harshad Nagadia
Summary: This study evaluated the quality of life of head and neck cancer survivors after surgical treatment, specifically focusing on eating-related concerns. Factors such as advanced tumor stage, extent of surgery, and adjuvant treatment were found to be associated with lower overall health scores. Improvement in quality of life was observed in previous studies after one year.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Suvina Amin, Seongjung Joo, Sandra Nolte, Hyun Kyoo Yoo, Nikunj Patel, Hilary F. Byrnes, Sara Costa-Cabral, Colin D. Johnson
Summary: This study systematically derived reference values for health-related quality of life (HRQoL) in metastatic pancreatic cancer (mPC) patients and found that patients in the POLO trial had better HRQoL scores compared to the literature and similar to the general population. These findings suggest the potential impact of prior treatment and resolution of chemotherapy-related symptoms on HRQoL in mPC patients.
Article
Oncology
Abigirl Machingura, Mekdes Taye, Jammbe Musoro, Jolie Ringash, Madeline Pe, Corneel Coens, Francesca Martinelli, Dongsheng Tu, Ethan Basch, Yvonne Brandberg, Mogens Gronvold, Alexander Eggermont, Fatima Cardoso, Jan Van Meerbeeck, Winette T. A. van der Graaf, Martin Taphoorn, Jaap C. Reijneveld, Riccardo Soffietti, Jeff Sloan, Galina Velikova, Henning Flechtner, Andrew Bottomley
Summary: This study validated prior findings and confirmed that the QLQ-C30 scales can be grouped into three main clusters. The results demonstrated that these clusters are consistent across different cancer types and patient characteristics.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Medicine, General & Internal
James W. F. Catto, Pramit Khetrapal, Federico Ricciardi, Gareth Ambler, Norman R. Williams, Tarek Al-Hammouri, Muhammad Shamim Khan, Ramesh Thurairaja, Rajesh Nair, Andrew Feber, Simon Dixon, Senthil Nathan, Tim Briggs, Ashwin Sridhar, Imran Ahmad, Jaimin Bhatt, Philip Charlesworth, Christopher Blick, Marcus G. Cumberbatch, Syed A. Hussain, Sanjeev Kotwal, Anthony Koupparis, John McGrath, Aidan P. Noon, Edward Rowe, Nikhil Vasdev, Vishwanath Hanchanale, Daryl Hagan, Chris Brew-Graves, John D. Kelly
Summary: This study compared the recovery and morbidity of patients undergoing robot-assisted radical cystectomy with intracorporeal reconstruction versus open radical cystectomy for bladder cancer. The results showed that robot-assisted surgery resulted in a statistically significant increase in the number of days alive and out of the hospital within 90 days of surgery. In addition, robot-assisted surgery had lower rates of thromboembolic and wound complications compared to open surgery. Patients who underwent robot-assisted surgery also reported better quality of life and less disability compared to those who underwent open surgery.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Oncology
O. Sjokvist, S. Hakansson, E. Pantiora, A. Karakatsanis
Summary: The study revealed that the HRQoL reference values for the outpatient breast clinic population were lower, with more severe symptoms and lower functionality compared to the general population. This suggests that the reference values may not accurately reflect the quality of life of the study population.
Article
Public, Environmental & Occupational Health
Micha J. Pilz, Eva-Maria Gamper, Fabio Efficace, Juan Arraras, Sandra Nolte, Gregor Liegl, Matthias Rose, Johannes M. Giesinger
Summary: This study provides normative values for the EORTC QLQ-30 questionnaire specifically for the general Italian population, which can be used to interpret quality of life profiles in Italian cancer patients. The results highlight the significant impact of health conditions on EORTC QLQ-C30 scores and emphasize the importance of adjusting for comorbidities when interpreting quality of life data.
Article
Nutrition & Dietetics
Elwira Gliwska, Dominika Glabska, Zuzanna Zaczek, Jacek Sobocki, Dominika Guzek
Summary: Patients with cancers of the head and neck and upper gastrointestinal tract are susceptible to malnutrition, which impacts their quality of life. Factors such as weight loss, group type, and age play a significant role in influencing patients' quality of life.
Article
Social Sciences, Interdisciplinary
Linda Dirven, Morten Aa Petersen, Neil K. Aaronson, Wei-Chu Chie, Thierry Conroy, Anna Costantini, Eva Hammerlid, Galina Velikova, Irma M. Verdonck-de Leeuw, Teresa Young, Mogens Groenvold
Summary: The study developed and evaluated an 8-item CAT-SL item bank for precise and efficient measurement of insomnia, which showed greater measurement precision compared to the original QLQ-C30 insomnia item and could result in a saving in sample size of approximately 15-25%.
APPLIED RESEARCH IN QUALITY OF LIFE
(2021)
Article
Endocrinology & Metabolism
Susanne Singer, Akram Al-Ibraheem, Monica Pinto, Ioannis Iakovou, Arild Andre Osthus, Eva Hammerlid, Laura Deborah Locati, Eva Gamper, Juan J. Ignacio, Susan Jordan, Naomi Kiyota, Matthias Buettner, Deborah Engesser, Rita Canotilho, Georgios Ioannidis, Olga Husson, Ricardo Ribeiro Gama, Giuseppe Fanetti, Laura Moss, Johanna Inhestern, Guy Andry, Dagmar Fuehrer, Dagmara Kulis, Harald Rimmele, Gerasimos Sykiotis, EORTC Quality Life Grp, EORTC Head Neck Canc Grp, EORTC Endocrine Tumours Grp
Summary: The purpose of this study was to validate the new European Organisation for Research and Treatment of Cancer Quality of Life Thyroid Cancer Module (EORTC QLQ-THY34). Through a survey of 437 thyroid cancer patients from 17 countries, it was found that the questionnaire has good internal consistency, discriminant validity, and test-retest reliability. The results show that the EORTC QLQ-THY34 questionnaire is a reliable and valid tool for measuring the quality of life in thyroid cancer patients.
Review
Oncology
Alexander Kretschmer, Roderick C. N. van den Bergh, Alberto Martini, Giancarlo Marra, Massimo Valerio, Igor Tsaur, Isabel Heidegger, Veeru Kasivisvanathan, Claudia Kesch, Felix Preisser, Christian D. Fankhauser, Fabio Zattoni, Francesco Ceci, Jonathan Olivier, Peter Chiu, Ignacio Puche-Sanz, Constance Thibault, Giorgio Gandaglia, Derya Tilki
Summary: This comprehensive review discusses the importance of health-related quality of life (HRQOL) for patients with advanced prostate cancer and the tools used to evaluate it in recent trials. Despite the growing evidence of oncological benefits from new therapies, there is still a lack of HRQOL-associated evidence for these patients.
Article
Health Care Sciences & Services
Takuya Kawahara, Naruto Taira, Takeru Shiroiwa, Yasuhiro Hagiwara, Takashi Fukuda, Yukari Uemura, Hirofumi Mukai
Summary: This study aimed to establish minimal important differences (MIDs) for the EORTC QLQ-C30 in patients with metastatic breast cancer. Using data from a randomized clinical trial, we estimated MIDs for 8 scales of the QLQ-C30. Patient-reported anchors were found to be more sensitive to early changes in health status.
QUALITY OF LIFE RESEARCH
(2022)
Article
Health Care Sciences & Services
Claudia Hartmann, Felix Fischer, Christoph P. Klapproth, Robert Roehle, Matthias Rose, Maria M. Karsten
Summary: In this study, PROMIS-29 and EORTC QLQ-C30 were compared in terms of their scores and conceptual agreement in the assessment of health-related quality of life. The results showed that both instruments had similar scores and satisfactory agreement in conceptional and statistical analysis. This suggests that they can be made more comparable through the development of score transformation algorithms or calibration on common scales.
QUALITY OF LIFE RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Muhammad Salman, Zia Ul Mustafa, Muhammad Husnnain Raza, Tahir Mehmood Khan, Noman Asif, Humera Tahir, Naureen Shehzadi, Tauqeer Hussain Mallhi, Yusra Habib Khan, Kishwar Sultana, Fahad Saleem, Khalid Hussain
Summary: This study investigated the psychological impacts of COVID-19 on Pakistani healthcare workers and their coping strategies. The findings showed a considerable proportion of healthcare workers experiencing anxiety and depression, with females and frontline workers being more affected. The most frequently adopted coping strategies were religious coping, acceptance, and coping planning.
DISASTER MEDICINE AND PUBLIC HEALTH PREPAREDNESS
(2022)
Article
Multidisciplinary Sciences
Zuhaib Ahmad, Muhammad Naeem, Rashid Azad, Izhar Hussain, Rehana Bibi, Maid Zaman, Rasheed Akbar, Nousheen Zafeer, Rehab Omer Elnour Elgezouly, Ghulam Mustafa, Muhammad Hasnain, Waqar Jaleel, Qaiser Shakeel, Fahad Saleem, Hamed A. Ghramh, Khalid Ali Khan
Summary: In this study, extensive field surveys were conducted in the Pothohar region of Pakistan to explore the diversity of assassin bugs and their habitats and prey records. The results showed uneven distribution of assassin bug species in the region, with some areas in Islamabad, Rawalpindi, and Jehlum exhibiting high diversity indices. Certain assassin bug species were found to be effective predators of economically important pests in various crops.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Public, Environmental & Occupational Health
Rabia Ishaq, Maryam Shoaib, Nosheen Sikander Baloch, Abdul Sadiq, Abdul Raziq, Zil E. Huma, Shanaz Raza, Fakhra Batool, Sajjad Haider, Fahad Saleem, Nafees Ahmad, Qaiser Iqbal, Amer Hayat Khan
Summary: This study described the quality of life of pregnant women during physiological pregnancy in Pakistan and identified education level and trimester as predictors of QoL. Healthcare professionals and policymakers should consider these factors when designing interventions for pregnant women.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Muhammad Shoaib, Abdul Raziqid, Qaiser Iqbal, Fahad Saleem, Sajjad Haider, Rabia Ishaq, Zaffar Iqbal, Mohammad Bashaar
Summary: This study examined the disposal practices of unused and expired pharmaceuticals among the general public in Quetta city, Pakistan. The findings revealed improper storage and disposal of medications, raising serious concerns. The study calls for immediate action to promote awareness and strengthen the pharmaceutical waste management program at the societal level.
Article
Medicine, General & Internal
Muhammad Kashif Habib, Muhammad Naeem Khan, Abdul Sadiq, Qaiser Iqbal, Abdul Raziq, Nafees Ahmad, Zaffar Iqbal, Sajjad Haider, Muhammad Anwar, Fazal Ur Rehman Khilji, Fahad Saleem, Amer Hayat Khan
Summary: This study aims to explore physicians' perceptions, experiences, and expectations of medication errors when managing patients with Type 2 Diabetes Mellitus. Through face-to-face interviews, it was found that medication errors were encountered by physicians, and they believed that understanding guidelines and reporting systems is essential. Recommendations include targeted training, establishment of an independent unit, and strict supervision to reduce medication errors.
FRONTIERS IN MEDICINE
(2022)
Article
Health Care Sciences & Services
Sajjad Haider, Fahad Saleem, Nafees Ahmad, Qaiser Iqbal, Mohammad Bashaar
Summary: The study aimed to examine the psychometric properties of the Urdu version of the Diabetes Quality-of-Life Brief Clinical Inventory. Through translation and validation processes, the study found that the translated version, DQoL-BCI-U, is a valid instrument in regions where Urdu is commonly spoken.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2022)
Article
Education, Scientific Disciplines
Syed Wasif Gillani, Ammar A. Siddiqui, Riham Elshafie, Hassaan Anwer Rathore
Summary: The study evaluated the impact of classroom versus online MOODLE-based teaching on research skills in pharmacy students. The findings suggested that the OSLE method is an effective tool for assessing knowledge and understanding, but MOODLE-based learning had a negative impact on self-reflection.
PHARMACY EDUCATION
(2022)
Article
Environmental Sciences
Nour Hisham Al-Ziftawi, Mohammed Fasihul Alam, Shereen Elazzazy, Asrul Akmal Shafie, Anas Hamad, Mohamed Izham Mohamed Ibrahim
Summary: This study compared the cost-effectiveness of palbociclib and ribociclib in Qatar, and found that ribociclib was superior to palbociclib in terms of costs, life-years gained, and quality-adjusted life-years gained, making it a cost-saving option for HR+/HER-2 negative stage IV breast cancer patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Immunology
Asrul Akmal Shafie, Edson Duarte Moreira, Alberta Di Pasquale, Dirk Demuth, Joanne Yoong Su Yin
Summary: This study surveyed a representative adult population in Argentina, Brazil, Colombia, Mexico, Indonesia, Malaysia, and Singapore to assess their willingness to uptake dengue vaccines and their knowledge, attitudes, and practices towards dengue, vector control, prevention, and vaccination. The results showed low global scores for knowledge (48%) and practice (44%), and a moderate score for attitude (66%), with comparable scores across countries. Among all respondents, 53% had a high willingness to vaccinate against dengue, with higher willingness in Latin America (59%) than in Asia Pacific (40%). Key factors associated with increased willingness included accessibility to public vaccination and trust in the healthcare system and government. A common approach to dengue prevention across endemic countries, with country-specific customization, may reduce dengue burden and improve outcomes.
Review
Health Care Sciences & Services
Sivaraj Raman, Asrul Akmal Shafie, Bee Ying Tan, Mannil Thomas Abraham, Shim Chen Kiong, Sok Ching Cheong
Summary: This systematic review compares the outcomes and design of economic evaluations for oral cancer screening programs. Out of 362 studies, 28 were evaluated and 6 were finally reviewed. Most screening initiatives were found to be cost-effective, but inter-study comparisons remained ambiguous. Modeling approaches may provide a practical and robust solution for evaluating the cost-effectiveness of oral cancer screening.
Article
Public, Environmental & Occupational Health
Ai Chi Liew, Asrul Akmal Shafie, Bee Ying Tan
ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH
(2023)
Article
Infectious Diseases
Maryam Farooqui, Zaffar Iqbal, Abdul Sadiq, Abdul Raziq, Mohammed Salem Alshammari, Qaiser Iqbal, Sajjad Haider, Fahad Saleem
Summary: Suboptimal antibiotics use and the development of antibiotic resistance is a universal calamity. This study aimed to evaluate hospital pharmacists' understanding of antibiotic use and resistance in a public healthcare institute in Quetta city, Pakistan. The findings showed that the hospital pharmacists had a good understanding of antibiotic use and resistance, and were willing to take measures to address this issue. The results of this study should be disseminated to policymakers and prescribers to tackle the problem of antibiotic use and resistance in developing countries like Pakistan.
Article
Health Care Sciences & Services
Nazir Ahmed, Fehmida Umar, Fahad Saleem, Qaiser Iqbal, Sallad Haider, Mohammad Bashaar
Summary: This study aimed to assess treatment outcomes and associated factors among children aged 6-59 months with severe acute malnutrition. The results showed a low recovery rate, with diarrhea and the use of amoxicillin being significant predictors of treatment outcomes. Therefore, strengthening community-based educational campaigns and enhancing the capacity of the outpatient therapeutic feeding program, as well as frequent monitoring and program evaluation, are recommended to reduce the frequency of severe acute malnutrition among children.
JOURNAL OF MULTIDISCIPLINARY HEALTHCARE
(2023)
Article
Health Policy & Services
Ghada Ben Salah, Maryam Farooqui, Mohammed Salem Alshammari, Abir Elghazali, Lamyaa Kassem, Nada Ibrahim, Imen Ben Abdelmalek, Muhammad Kamran Rasheed
Summary: Despite the lack of scientific evidence, complementary and alternative medicine (CAM) is commonly used by patients with chronic kidney disease (CKD) in Saudi Arabia. This study aimed to evaluate the prevalence, types, and non-disclosure of CAM use among CKD patients and kidney transplant recipients in Saudi Arabia.
JOURNAL OF PHARMACEUTICAL POLICY AND PRACTICE
(2023)
Article
Public, Environmental & Occupational Health
Fareed Khan, Muhammad Anwar, Rabia Ishaq, Qaiser Iqbal, Sajjad Haider, Abdul Raziq, Abdul Malik Tareen, Mohammad Alam Mengal, Syed Umer Jan, Fahad Saleem
Summary: This study aimed to assess the understanding of health supplement use in patients with chronic diseases in Quetta, Pakistan. The results showed that most patients had inadequate understanding of health supplements, as they did not discuss their use with healthcare professionals and were unaware of safety concerns, interactions, and side effects. Education and disease state were found to be associated with patients' understanding.
JOURNAL OF PUBLIC HEALTH-HEIDELBERG
(2023)
