Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy

UBA1: At the Crossroads of Ubiquitin Homeostasis and Neurodegeneration

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Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

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Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target

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Neurotransmitter release in motor nerve terminals of a mouse model of mild spinal muscular atrophy

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Anatomy and function of cholinergic C bouton inputs to motor neurons

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Spinal muscular atrophy: a motor neuron disorder or a multi-organ disease?

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Na+/K+ ATPase  1 and  3 Isoforms Are Differentially Expressed in  - and  -Motoneurons

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Selective Vulnerability of Spinal and Cortical Motor Neuron Subpopulations in delta7 SMA Mice

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Cytoarchitecture of the Spinal Cord of the Postnatal (P4) Mouse

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Spinal muscular atrophy: The role of SMN in axonal mRNA regulation

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Wnt7A Identifies Embryonic  -Motor Neurons and Reveals Early Postnatal Dependence of  -Motor Neurons on a Muscle Spindle-Derived Signal

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Fiji: an open-source platform for biological-image analysis

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Morphological Characteristics of Motor Neurons Do Not Determine Their Relative Susceptibility to Degeneration in a Mouse Model of Severe Spinal Muscular Atrophy

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Spinal muscular atrophy: going beyond the motor neuron

(2012) Gillian Hamilton et al.   TRENDS IN MOLECULAR MEDICINE

The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy

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Reversible molecular pathology of skeletal muscle in spinal muscular atrophy

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Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy

(2011) K. K. Y. Ling et al.   HUMAN MOLECULAR GENETICS

Osteopontin is an alpha motor neuron marker in the mouse spinal cord

(2011) Hidemi Misawa et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy

(2011) George Z. Mentis et al.   NEURON

Cholinergic partition cells and lamina X neurons induce a muscarinic-dependent short-term potentiation of commissural glutamatergic inputs in lumbar motoneurons

(2011) Sandrine S. Bertrand   Frontiers in Neural Circuits

Motor Neuron Diversity in Development and Disease

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Spinal Muscular Atrophy: New and Emerging Insights from Model Mice

(2010) Gyu-Hwan Park et al.   Current Neurology and Neuroscience Reports

SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy

(2010) Markus Riessland et al.   HUMAN MOLECULAR GENETICS

Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice

(2010) Christopher R. Heier et al.   HUMAN MOLECULAR GENETICS

Monosynaptic Rabies Virus Reveals Premotor Network Organization and Synaptic Specificity of Cholinergic Partition Cells

(2010) Anna E. Stepien et al.   NEURON

Synaptic Defects in the Spinal and Neuromuscular Circuitry in a Mouse Model of Spinal Muscular Atrophy

(2010) Karen K. Y. Ling et al.   PLoS One

Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival

(2009) Neil A Shneider et al.   Neural Development

Gamma and alpha motor neurons distinguished by expression of transcription factor Err3

(2009) A. Friese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy

(2008) Shingo Kariya et al.   HUMAN MOLECULAR GENETICS

Spinal muscular atrophy

(2008) Mitchell R Lunn et al.   LANCET