Unresolved Questions in Rheumatology: Motion for Debate: Osteoarthritis Clinical Trials Have Not Identified Efficacious Therapies Because Traditional Imaging Outcome Measures Are Inadequate

Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial

(2012) Laura Louise Laslett et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

(2012) Jean-Yves Reginster et al.   ANNALS OF THE RHEUMATIC DISEASES

In normal knees, joint space width (JSW) is correlated with the intermargin distance (IMD), a measure of medial tibial plateau alignment. Variations in IMD explain variability in JSW in serial radiographs

(2012) Catherine Mercier et al.   JOINT BONE SPINE

Meniscus pathology, osteoarthritis and the treatment controversy

(2012) Martin Englund et al.   Nature Reviews Rheumatology

Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral joint – the MOST study

(2012) F.W. Roemer et al.   OSTEOARTHRITIS AND CARTILAGE

Bone marrow lesions in knee osteoarthritis change in 6–12 weeks

(2012) D.T. Felson et al.   OSTEOARTHRITIS AND CARTILAGE

Influence of variation in semiflexed knee positioning during image acquisition on separate quantitative radiographic parameters of osteoarthritis, measured by Knee Images Digital Analysis

(2012) M.B. Kinds et al.   OSTEOARTHRITIS AND CARTILAGE

Three-dimensional turbo spin-echo magnetic resonance imaging (MRI) and semiquantitative assessment of knee osteoarthritis: comparison with two-dimensional routine MRI

(2012) M.D. Crema et al.   OSTEOARTHRITIS AND CARTILAGE

Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative

(2012) W. Wirth et al.   OSTEOARTHRITIS AND CARTILAGE

Prevalence of abnormalities in knees detected by MRI in adults without knee osteoarthritis: population based observational study (Framingham Osteoarthritis Study)

(2012) A. Guermazi et al.   BMJ-British Medical Journal

Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI

(2011) L. M. Wildi et al.   ANNALS OF THE RHEUMATIC DISEASES

Differences in multijoint radiographic osteoarthritis phenotypes among African Americans and Caucasians: The Johnston County Osteoarthritis Project

(2011) Amanda E. Nelson et al.   ARTHRITIS AND RHEUMATISM

Risk factors for magnetic resonance imaging-detected patellofemoral and tibiofemoral cartilage loss during a six-month period: The Joints On Glucosamine study

(2011) Frank W. Roemer et al.   ARTHRITIS AND RHEUMATISM

Prevalence of magnetic resonance imaging-defined atrophic and hypertrophic phenotypes of knee osteoarthritis in a population-based cohort

(2011) Frank W. Roemer et al.   ARTHRITIS AND RHEUMATISM

Quantitative bone marrow lesion size in osteoarthritic knees correlates with cartilage damage and predicts longitudinal cartilage loss

(2011) Jeffrey B Driban et al.   BMC MUSCULOSKELETAL DISORDERS

Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial

(2011) Cyrus Cooper et al.   CURRENT MEDICAL RESEARCH AND OPINION

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

64 ORAL CALCITONIN DEMONSTRATED SYMPTOM-MODIFYING EFFICACY AND INCREASED CARTILAGE VOLUME: RESULTS FROM A 2-YEAR PHASE 3 TRIAL IN PATIENTS WITH OSTEOARTHRITIS OF THE KNEE

(2011) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolysate: a pilot randomized controlled trial

(2011) T.E. McAlindon et al.   OSTEOARTHRITIS AND CARTILAGE

Summary and recommendations of the OARSI FDA osteoarthritis Assessment of Structural Change Working Group

(2011) P.G. Conaghan et al.   OSTEOARTHRITIS AND CARTILAGE

Responsiveness and reliability of MRI in knee osteoarthritis: a meta-analysis of published evidence

(2011) D.J. Hunter et al.   OSTEOARTHRITIS AND CARTILAGE

Assessment of synovitis with contrast-enhanced MRI using a whole-joint semiquantitative scoring system in people with, or at high risk of, knee osteoarthritis: the MOST study

(2010) A. Guermazi et al.   ANNALS OF THE RHEUMATIC DISEASES

Do knee abnormalities visualised on MRI explain knee pain in knee osteoarthritis? A systematic review

(2010) E. Yusuf et al.   ANNALS OF THE RHEUMATIC DISEASES

Fluctuation of knee pain and changes in bone marrow lesions, effusions, and synovitis on magnetic resonance imaging

(2010) Yuqing Zhang et al.   ARTHRITIS AND RHEUMATISM

Alignment of the medial tibial plateau affects the rate of joint space narrowing in the osteoarthritic knee

(2010) E. Vignon et al.   OSTEOARTHRITIS AND CARTILAGE

Treatment of Symptomatic Cartilage Defects of the Knee

(2009) Daniel B. F. Saris et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Methodology and statistical analysis in the Glucosamine/Chondroitin Arthritis Intervention Trial: Comment on the article by Sawitzke et al

(2009) Kenneth D. Brandt et al.   ARTHRITIS AND RHEUMATISM

OA clinical trials: current targets and trials for OA. Choosing molecular targets: what have we learned and where we are headed?

(2009) M.-P. Hellio Le Graverand-Gastineau   OSTEOARTHRITIS AND CARTILAGE

Pre-radiographic MRI findings are associated with onset of knee symptoms: the most study

(2009) M.K. Javaid et al.   OSTEOARTHRITIS AND CARTILAGE

Radiographic-Based Grading Methods and Radiographic Measurement of Joint Space Width in Osteoarthritis

(2009) Marie-Pierre Hellio Le Graverand et al.   RADIOLOGIC CLINICS OF NORTH AMERICA

Tibiofemoral Joint Osteoarthritis: Risk Factors for MR-depicted Fast Cartilage Loss over a 30-month Period in the Multicenter Osteoarthritis Study

(2009) Frank W. Roemer et al.   RADIOLOGY

Commentary: Is It Useful to Subset “Primary” Osteoarthritis? A Critique Based on Evidence Regarding the Etiopathogenesis of Osteoarthritis

(2009) Kenneth D. Brandt et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI

(2008) J-P Raynauld et al.   ANNALS OF THE RHEUMATIC DISEASES

Head-to-head comparison of the Lyon Schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees

(2008) M-P H. Le Graverand et al.   ANNALS OF THE RHEUMATIC DISEASES

Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls: a multicentre study using 3.0 Tesla MRI and Lyon-Schuss radiography

(2008) M-P H. Le Graverand et al.   ANNALS OF THE RHEUMATIC DISEASES

The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: A report from the glucosamine/chondroitin arthritis intervention trial

(2008) Allen D. Sawitzke et al.   ARTHRITIS AND RHEUMATISM

Etiopathogenesis of Osteoarthritis

(2008) Kenneth D. Brandt et al.   MEDICAL CLINICS OF NORTH AMERICA