Enhanced Rho-Associated Protein Kinase Activation in Patients With Systemic Lupus Erythematosus

The therapeutic effects of Rho-ROCK inhibitors on CNS disorders

(2016) Takekazu Kubo   Therapeutics and Clinical Risk Management

ROCKs as immunomodulators of stroke

(2012) Qing Mei Wang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Administration of fasudil, a ROCK inhibitor, attenuates disease in lupus-prone NZB/W F1 female mice

(2012) RA Stirzaker et al.   LUPUS

Accelerated atherosclerosis in patients with SLE—mechanisms and management

(2012) Brian J. Skaggs et al.   Nature Reviews Rheumatology

Regulation of Atherogenesis by Chemokine Receptor CCR6

(2012) Wuzhou Wan et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Rho-kinase: important new therapeutic target in cardiovascular diseases

(2011) Kimio Satoh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

(2011) Richard Furie et al.   ARTHRITIS AND RHEUMATISM

Simvastatin Inhibits IFN Regulatory Factor 4 Expression and Th17 Cell Differentiation in CD4+ T Cells Derived from Patients with Multiple Sclerosis

(2011) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

The Dysregulation of Cytokine Networks in Systemic Lupus Erythematosus

(2011) Sokratis A. Apostolidis et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease

(2011) Qian Zhou et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

(2010) Corinna E. Weckerle et al.   ARTHRITIS AND RHEUMATISM

An immune paradox: How can the same chemokine axis regulate both immune tolerance and activation?

(2010) Iain Comerford et al.   BIOESSAYS

Pleiotropic Effects of Statins

(2010) Qian Zhou et al.   CIRCULATION JOURNAL

Rho kinase inhibition in diabetic nephropathy

(2010) Radko Komers   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice

(2010) Partha S. Biswas et al.   JOURNAL OF CLINICAL INVESTIGATION

Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus

(2010) Silvia N Kariuki et al.   ARTHRITIS RESEARCH & THERAPY

Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

(2010) Kamini Shah et al.   ARTHRITIS RESEARCH & THERAPY

Th17 and natural Treg cell population dynamics in systemic lupus erythematosus

(2009) Ji Yang et al.   ARTHRITIS AND RHEUMATISM

Th17 cells in rheumatoid arthritis and systemic lupus erythematosus

(2009) A. B. Pernis   JOURNAL OF INTERNAL MEDICINE

Increased serum interleukin 17 in patients with systemic lupus erythematosus

(2009) Xue-Fei Zhao et al.   MOLECULAR BIOLOGY REPORTS

Subclinical Atherosclerosis in Rheumatoid Arthritis and Systemic Lupus Erythematosus

(2008) Jane E. Salmon et al.   AMERICAN JOURNAL OF MEDICINE

Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus

(2008) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Rho GTPase-mediated pathways in mature CD4+ T cells

(2008) Alessandra B. Pernis   AUTOIMMUNITY REVIEWS

Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: Implications for Th17-mediated inflammation in auto-immunity

(2008) Chun Kwok Wong et al.   CLINICAL IMMUNOLOGY

IL-17 and the Th17 lineage in systemic lupus erythematosus

(2008) Lee Ann Garrett-Sinha et al.   CURRENT OPINION IN RHEUMATOLOGY