Bach1 regulates osteoclastogenesis in a mouse model via both heme oxygenase 1-dependent and heme oxygenase 1-independent pathways

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2

(2011) M. Watanabe-Matsui et al.   BLOOD

Role of oxidative stress in rheumatoid arthritis: insights from the Nrf2-knockout mice

(2010) C. J. Wruck et al.   ANNALS OF THE RHEUMATIC DISEASES

Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction

(2010) So Youn Park et al.   ARTHRITIS AND RHEUMATISM

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

The increased in vitro osteoclastogenesis in patients with rheumatoid arthritis is due to increased percentage of precursors and decreased apoptosis — The In Vitro Osteoclast Differentiation in Arthritis (IODA) study

(2010) M. Durand et al.   BONE

Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1

(2010) Takuya Miyazaki et al.   CANCER SCIENCE

Histomorphometric Analysis Reveals Reduced Bone Mass and Bone Formation in Patients With Quiescent Crohn's Disease

(2010) Angela E. Oostlander et al.   GASTROENTEROLOGY

RANKL-mediated Reactive Oxygen Species Pathway That Induces Long Lasting Ca2+Oscillations Essential for Osteoclastogenesis

(2010) Min Seuk Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Blimp1-mediated repression of negative regulators is required for osteoclast differentiation

(2010) K. Nishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of denosumab on bone mineral density and bone turnover in patients with rheumatoid arthritis receiving concurrent glucocorticoids or bisphosphonates

(2009) R. K. Dore et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-12 inhibits TNF-α induced osteoclastogenesis via a T cell-independent mechanism in vivo

(2009) Masako Yoshimatsu et al.   BONE

Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1–NRF2 pathway, and not the BACH1–NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds

(2009) A.Kenneth MacLeod et al.   CARCINOGENESIS

Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: Role of IL-6

(2009) Takuya Tanimoto et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant-induced Phosphorylation of Tyrosine 486 Leads to Rapid Nuclear Export of Bach1 That Allows Nrf2 to Bind to the Antioxidant Response Element and Activate Defensive Gene Expression

(2009) James W. Kaspar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The  -Isoform of p38 MAPK Specifically Regulates Arthritic Bone Loss

(2009) C. Bohm et al.   JOURNAL OF IMMUNOLOGY

Osteoimmunology and the effects of the immune system on bone

(2009) Hiroshi Takayanagi   Nature Reviews Rheumatology

HMOX1promoter polymorphism modulates the relationship between disease activity and joint damage in rheumatoid arthritis

(2008) Frank A. D. T. G. Wagener et al.   ARTHRITIS AND RHEUMATISM

Myocardial Protection Against Pressure Overload in Mice Lacking Bach1, a Transcriptional Repressor of Heme Oxygenase-1

(2008) Shinji Mito et al.   HYPERTENSION

Ablation of the Bach1 Gene Leads to the Suppression of Atherosclerosis in Bach1 and Apolipoprotein E Double Knockout Mice

(2008) Yuichiro Watari et al.   HYPERTENSION RESEARCH

Heme oxygenase 1 attenuates the development of atopic dermatitis–like lesions in mice: Implications for human disease

(2008) Mio Kirino et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes

(2008) Anna Yarilina et al.   NATURE IMMUNOLOGY