Treatment of arthritis by macrophage depletion and immunomodulation: Testing an apoptosis-mediated therapy in a humanized death receptor mouse model

Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice

(2011) Hui-Chen Hsu et al.   ARTHRITIS AND RHEUMATISM

Regulation of systemic and local myeloid cell subpopulations by bone marrow cell-derived granulocyte-macrophage colony-stimulating factor in experimental inflammatory arthritis

(2011) Andrew D. Cook et al.   ARTHRITIS AND RHEUMATISM

IFN-γ directly inhibits TNF-α-induced osteoclastogenesis in vitro and in vivo and induces apoptosis mediated by Fas/Fas ligand interactions

(2011) Haruka Kohara et al.   IMMUNOLOGY LETTERS

Mechanisms of Drug Sensitization to TRA-8, an Agonistic Death Receptor 5 Antibody, Involve Modulation of the Intrinsic Apoptotic Pathway in Human Breast Cancer Cells

(2011) H. M. Amm et al.   MOLECULAR CANCER RESEARCH

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture

(2010) Hans P. Kiener et al.   ARTHRITIS AND RHEUMATISM

Phase I Trial of Weekly Tigatuzumab, an Agonistic Humanized Monoclonal Antibody Targeting Death Receptor 5 (DR5)

(2010) Andres Forero-Torres et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

B Cell Therapies for Rheumatoid Arthritis: Beyond B cell Depletion

(2010) Ismael Calero et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

(2009) Laura E Edgington et al.   NATURE MEDICINE

Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis

(2009) P. Hillyer et al.   RHEUMATOLOGY

Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis

(2009) K. Nistala et al.   RHEUMATOLOGY

IL-23 in the Pathogenesis of Rheumatoid Arthritis

(2009) A. Paradowska-Gorycka et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis

(2008) Paul J. Egan et al.   ARTHRITIS AND RHEUMATISM

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

(2008) H. J. P. M. Koenen et al.   BLOOD

Gr1+ Inflammatory Monocytes Are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii

(2008) Ildiko R. Dunay et al.   IMMUNITY

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

(2008) Clare A. Notley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Protocol for the induction of arthritis in C57BL/6 mice

(2008) Julia J Inglis et al.   Nature Protocols

Breast Tumor Xenografts: Diffusion-weighted MR Imaging to Assess Early Therapy with Novel Apoptosis-Inducing Anti-DR5 Antibody

(2008) Hyunki Kim et al.   RADIOLOGY