Brief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupus

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

(2011) Timothy B Niewold et al.   ANNALS OF THE RHEUMATIC DISEASES

Interferon Alpha as a Primary Pathogenic Factor in Human Lupus

(2011) Timothy B. Niewold   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

(2010) Corinna E. Weckerle et al.   ARTHRITIS AND RHEUMATISM

IFN Regulatory Factor 5 Is Required for Disease Development in the Fc RIIB-/-Yaa and Fc RIIB-/- Mouse Models of Systemic Lupus Erythematosus

(2009) C. Richez et al.   JOURNAL OF IMMUNOLOGY

Disease progression in mothers of children enrolled in the Research Registry for Neonatal Lupus

(2008) T L Rivera et al.   ANNALS OF THE RHEUMATIC DISEASES

Serum type I interferon activity is dependent on maternal diagnosis in anti-SSA/Ro–positive mothers of children with neonatal lupus

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

(2008) G Nordmark et al.   GENES AND IMMUNITY