Endogenous activation of adaptive immunity: Tenascin-C drives interleukin-17 synthesis in murine arthritic joint disease

Immunotherapy of Rheumatoid Arthritis Targeting Inflammatory Cytokines and Autoreactive T Cells

(2010) Guangjie Chen   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Extracellular Matrix of Glioblastoma Inhibits Polarization and Transmigration of T Cells: The Role of Tenascin-C in Immune Suppression

(2010) J.-Y. Huang et al.   JOURNAL OF IMMUNOLOGY

Transcriptional Regulation of the Endogenous Danger Signal Tenascin-C: A Novel Autocrine Loop in Inflammation

(2010) Fui G. Goh et al.   JOURNAL OF IMMUNOLOGY

The yin and yang of regulatory T cells and inflammation in RA

(2010) Clare A. Notley et al.   Nature Reviews Rheumatology

Aryl hydrocarbon receptor negatively regulates dendritic cell immunogenicity via a kynurenine-dependent mechanism

(2010) N. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

GATA-3 protects against severe joint inflammation and bone erosion and reduces differentiation of Th17 cells during experimental arthritis

(2009) Jan Piet van Hamburg et al.   ARTHRITIS AND RHEUMATISM

Targeting Toll-like Receptors in Autoimmunity

(2009) K. Midwood et al.   CURRENT DRUG TARGETS

Transcriptional regulatory networks in Th17 cell differentiation

(2009) Liang Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Diseases that may benefit from manipulating the Th17 pathway

(2009) Pierre Miossec   EUROPEAN JOURNAL OF IMMUNOLOGY

IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?

(2009) Partha S. Biswas et al.   IMMUNOLOGICAL REVIEWS

 9 Integrin and Its Ligands Constitute Critical Joint Microenvironments for Development of Autoimmune Arthritis

(2009) M. Kanayama et al.   JOURNAL OF IMMUNOLOGY

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo

(2009) Mandy J McGeachy et al.   NATURE IMMUNOLOGY

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

Are new agents needed to treat RA?

(2009) Peter E. Lipsky   Nature Reviews Rheumatology

IL-17 as a future therapeutic target for rheumatoid arthritis

(2009) Wim B. van den Berg et al.   Nature Reviews Rheumatology

Dendritic cells as targets for therapy in rheumatoid arthritis

(2009) Shaukat Khan et al.   Nature Reviews Rheumatology

Interleukin-17 as a drug target in human disease

(2009) Stefan Ivanov et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The role of tenascin-C in tissue injury and tumorigenesis

(2009) Kim S. Midwood et al.   Journal of Cell Communication and Signaling

Shift from toll-like receptor 2 (TLR-2) toward TLR-4 dependency in the erosive stage of chronic streptococcal cell wall arthritis coincident with TLR-4-mediated interleukin-17 production

(2008) Shahla Abdollahi-Roodsaz et al.   ARTHRITIS AND RHEUMATISM

The orchestra of toll-like receptors and their potential role in frequently occurring rheumatic conditions

(2008) Mieke F. Roelofs et al.   ARTHRITIS AND RHEUMATISM

Determination of T-cell fate by dendritic cells

(2008) Sandra S Diebold   IMMUNOLOGY AND CELL BIOLOGY

Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells

(2008) Fuping Zhang et al.   NATURE IMMUNOLOGY