Excessive interleukin-15 transpresentation endows NKG2D+CD4+ T cells with innate-like capacity to lyse vascular endothelium in granulomatosis with polyangiitis (Wegener's)

IL-15 trans-presentation by pulmonary dendritic cells promotes effector CD8 T cell survival during influenza virus infection

(2010) Jodi McGill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cellular immunity in Wegener's granulomatosis: Characterizing T lymphocytes

(2009) Annelies E. Berden et al.   ARTHRITIS AND RHEUMATISM

Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors

(2009) Y. T. Bryceson et al.   BLOOD

Activating NK-cell receptors co-stimulate CD4+CD28−T cells in patients with rheumatoid arthritis

(2009) Andreas E. R. Fasth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

(2009) Elsa-Noah N'Diaye et al.   JOURNAL OF CELL BIOLOGY

Normally occurring NKG2D+CD4+T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus

(2009) Zhenpeng Dai et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expansion of circulating NKG2D+ effector memory T-cells and expression of NKG2D-ligand MIC in granulomaous lesions in Wegener's granulomatosis

(2008) Dorin Capraru et al.   CLINICAL IMMUNOLOGY

IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation

(2008) Erwan Mortier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

(2008) Nicholas D. Huntington et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Essential Role of DAP12 Signaling in Macrophage Programming into a Fusion-Competent State

(2008) L. Helming et al.   Science Signaling